- Sequence-programmable covalent bonding of designed DNA assemblies
Site-specific ultraviolet “point welding” makes designed DNA objects much more durable.
- High-efficiency large-area perovskite photovoltaic modules achieved via electrochemically assembled metal-filamentary nanoelectrodes
We devised an electrochemical patterning process for large-area perovskite photovoltaic modules.
- Multivalent binding of herpesvirus to living cells is tightly regulated during infection
We probe herpesvirus binding to living cells using atomic force microscopy.
- Origami and 4D printing of elastomer-derived ceramic structures
The breakthroughs on origami and 4D printing of ceramics could turn a new page for structural application of ceramics.
- Three-level spaser for next-generation luminescent nanoprobe
Delayed spasing dots with ~3-nm spectral width, ~1 mJ cm−2 threshold, and ~102-μs lifetime were developed for a bionanoprobe.
- Superconducting cavity electro-optics: A platform for coherent photon conversion between superconducting and photonic circuits
Electro-optical chips promise a quantum link between electronic and optical circuits.
- Genome mapping of seed-borne allergens and immunoresponsive proteins in wheat
We present a comprehensive analysis of variation in genes and gene expression of allergens and immunoresponsive proteins in wheat.
- Mechanism of calmodulin inactivation of the calcium-selective TRP channel TRPV6
Cryo-EM structures of the epithelial calcium channel TRPV6-calmodulin complex reveal a mechanism of Ca2+-induced inactivation.
- Genetic regulation of mitotic competence in G0 quiescent cells
Among 85 genes that maintain mitotic competence in quiescent eukaryotic cells, Nem1 protects nuclei from autophagy by regulating lipin.
- Deep fluid pathways beneath Mammoth Mountain, California, illuminated by migrating earthquake swarms
Earthquakes beneath a Californian volcano track fluid movement and outline a zone of partial melt in the deep and mid-crust.
- Cross-disciplinary evolution of the genomics revolution
Pervasive cross-disciplinarity has been a key factor in the genomics revolution.
- Impacts of forests on children’s diet in rural areas across 27 developing countries
Nearby forests improve children’ diets in developing countries, and access to capital enhances the effect.
- DNA methylation regulates transcriptional homeostasis of algal endosymbiosis in the coral model Aiptasia
The epigenetic mechanism of DNA methylation optimizes gene expression in endosymbiosis between cnidarians and their microalgae.
About The Cover
COVER The emergence of synthetic biology as a defining technology of the 21st century motivates the need to inspire and train a new generation of scientists. However, implementing hands-on biology practices in teaching environments is challenging because specialized equipment and expertise is needed to grow living cells. Collins et al. and Jewett et al.developed BioBits™ Bright and Explorer, two shelf-stable, "just-add-water," synthetic biology education kits enabled using freeze-dried cell-free (FD-CF) reactions. BioBits™ kits are designed to engage the sense of sight, smell, and touch, costing less than $100 per 30-student classroom. The kits establish a new educational paradigm for implementing FD-CF reactions for use in classrooms and other low-resource environments. [CREDIT: MEGAN BELTRAN]