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  • N-doped carbon nanomaterials are durable catalysts for oxygen reduction reaction in acidic fuel cells
    BY JIANGLAN SHUI, MIN WANG, FENG DU, LIMING DAI | SCIENCE ADVANCES 27 Feb 2015: e1400129
    1. Jianglan Shui,
    2. Min Wang,
    3. Feng Du and
    4. Liming Dai*
    1. Center of Advanced Science and Engineering for Carbon (Case4Carbon), Department of Macromolecular Science Engineering, Case School of Engineering, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA.
    1. ↵*Corresponding author: E-mail: liming.dai{at}case.edu

    Carbon-based, metal-free catalysts showed excellent activity, durability and potential to replace Pt in acidic fuel cells.

    Keywords
    • Oxygen reduction
    • Metal-free catalysts
    • Carbon nanomaterials
    • PEM fuel cells

    This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommerical license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

  • Distinct plasma immune signatures in ME/CFS are present early in the course of illness
    BY MADY HORNIG, JOSÉ G. MONTOYA, NANCY G. KLIMAS, SUSAN LEVINE, DONNA FELSENSTEIN, LUCINDA BATEMAN, DANIEL L. PETERSON, C. GUNNAR GOTTSCHALK, ANDREW F. SCHULTZ, XIAOYU CHE, MEREDITH L. EDDY, ANTHONY L. KOMAROFF, W. IAN LIPKIN | SCIENCE ADVANCES 27 Feb 2015: e1400121
    1. Mady Hornig1,2,*,
    2. José G. Montoya3,
    3. Nancy G. Klimas4,
    4. Susan Levine5,
    5. Donna Felsenstein6,
    6. Lucinda Bateman7,
    7. Daniel L. Peterson8,
    8. C. Gunnar Gottschalk8,
    9. Andrew F. Schultz1,
    10. Xiaoyu Che1,
    11. Meredith L. Eddy1,
    12. Anthony L. Komaroff9 and
    13. W. Ian Lipkin1,2,10
    1. 1Center for Infection and Immunity, Columbia University Mailman School of Public Health, New York, NY 10032, USA.
    2. 2Department of Epidemiology, Columbia University Mailman School of Public Health, New York, NY 10032, USA.
    3. 3Stanford University, Palo Alto, CA 94305, USA.
    4. 4Institute for Neuro-Immune Medicine, College of Osteopathic Medicine, Nova Southeastern University, Fort Lauderdale, FL 33314, USA, and Miami VA Medical Center, Miami, FL 33125, USA.
    5. 5Levine Clinic, New York, NY 10021, USA.
    6. 6Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
    7. 7Fatigue Consultation Clinic, Salt Lake City, UT 84102, USA.
    8. 8Sierra Internal Medicine at Incline Village, Incline Village, NV 89451, USA.
    9. 9Harvard Medical School, Brigham and Women’s Hospital, Boston, MA 02115, USA.
    10. 10Departments of Neurology and Pathology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.
    1. ↵*Corresponding author. E-mail: mh2092{at}cumc.columbia.edu

    Cytokine alterations are more strongly correlated with illness duration than with measures of illness severity.

    Keywords
    • myalgic encephalomyelitis/chronic fatigue syndrome
    • immune signatures
    • cytokine regulation
    • illness duration
    • biomarkers

    This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommerical license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

  • Membrane alternatives in worlds without oxygen: Creation of an azotosome
    BY JAMES STEVENSON, JONATHAN LUNINE, PAULETTE CLANCY | SCIENCE ADVANCES 27 Feb 2015: e1400067
    1. James Stevenson1,
    2. Jonathan Lunine2 and
    3. Paulette Clancy1,*
    1. 1School of Chemical and Biomolecular Engineering, Cornell University, 365 Olin Hall, Ithaca, NY 14853, USA.
    2. 2Department of Astronomy, Cornell University, Ithaca, NY 14853, USA.
    1. ↵*Corresponding author. E-mail: Paulette.Clancy{at}cornell.edu

    Calculations show that these molecules form membrane-like structures at low temperatures in a liquid methane environment.

    Keywords
    • Titan
    • abiogenesis
    • exobiology
    • liposome
    • physical chemistry
    • quantum chemistry
    • computational chemistry
    • molecular dynamics

    This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommerical license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

  • Gelatin-derived sustainable carbon-based functional materials for energy conversion and storage with controllability of structure and component
    BY ZHONG-LI WANG, DAN XU, HAI-XIA ZHONG, JUN WANG, FAN-LU MENG, XIN-BO ZHANG | SCIENCE ADVANCES 27 Feb 2015: e1400035
    1. Zhong-Li Wang1,
    2. Dan Xu1,
    3. Hai-Xia Zhong1,2,
    4. Jun Wang1,2,
    5. Fan-Lu Meng1 and
    6. Xin-Bo Zhang1,*
    1. 1State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R. China.
    2. 2University of Chinese Academy of Sciences, Beijing 100049, P. R. China.
    1. ↵*Corresponding author. E-mail: xbzhang{at}ciac.ac.cn

    This synthetic approach produced catalysts with higher catalytic activity and better oxygen-reduction durability.

    Keywords
    • carbon materials
    • gelatin
    • non-precious catalysts
    • oxygen reduction reaction
    • lithium storage

    This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommerical license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

  • Myosin-binding protein C corrects an intrinsic inhomogeneity in cardiac excitation-contraction coupling
    BY MICHAEL J. PREVIS, BENJAMIN L. PROSSER, JI YOUNG MUN, SAMANTHA BECK PREVIS, JAMES GULICK, KYOUNGHWAN LEE, JEFFREY ROBBINS, ROGER CRAIG, W. J. LEDERER, DAVID M. WARSHAW | SCIENCE ADVANCES 20 Feb 2015: e1400205
    1. Michael J. Previs1,*,
    2. Benjamin L. Prosser2,*,
    3. Ji Young Mun3,4,*,
    4. Samantha Beck Previs1,
    5. James Gulick5,
    6. Kyounghwan Lee3,
    7. Jeffrey Robbins5,
    8. Roger Craig3,†,
    9. W. J. Lederer6,† and
    10. David M. Warshaw1,†
    1. 1Department of Molecular Physiology and Biophysics, Cardiovascular Research Institute of Vermont, The University of Vermont, Burlington, VT 05405, USA.
    2. 2Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
    3. 3Department of Cell and Developmental Biology, University of Massachusetts Medical School, Worcester, MA 01655, USA.
    4. 4Department of Biomedical Laboratory Science, College of Health Sciences, Eulji University, Seongnam-Si 461-701, Gyeonggi-Do, Republic of Korea.
    5. 5Department of Pediatrics and the Heart Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229, USA.
    6. 6Department of Physiology, Center for Biomedical Engineering and Technology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
    1. ↵†Corresponding author. E-mail: david.warshaw{at}uvm.edu (D.M.W.); jlederer{at}umaryland.edu (W.J.L.); roger.craig{at}umassmed.edu (R.C.)

    • ↵* These authors contributed equally to this work.

    The localization of MyBP-C within cardiac muscle cells provides efficient mechanochemical excitation-contraction coupling.

    Keywords
    • myosin-binding protein C
    • native thick filaments
    • native thin filaments
    • calcium dynamics
    • phosphorylation
    • muscle activation
    • muscle regulation
    • cardiac excitation-contraction coupling

    This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommerical license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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