- The demise of Angkor: Systemic vulnerability of urban infrastructure to climatic variations
The historic urban collapse of Angkor is linked to infrastructural complexity and climatic variability.
- GPR40 modulates epileptic seizure and NMDA receptor function
GPR40 modulates epileptic seizure and NMDA receptor function through the regulation of NR2A and NR2B surface expression.
- Prevention of pesticide-induced neuronal dysfunction and mortality with nucleophilic poly-Oxime topical gel
Topical gel reduces pesticide-induced systemic acetylcholinesterase inhibition, thus preventing neuronal dysfunction and mortality.
- New generation of U.S. satellite microwave sounder achieves high radiometric stability performance for reliable climate change detection
How accurate can satellite measure the climate trends in atmospheric temperatures?
- Global expansion of Mycobacterium tuberculosis lineage 4 shaped by colonial migration and local adaptation
Repeated emergence, not international dissemination, is behind the rise of multidrug-resistant lineage 4 tuberculosis.
- An enzymatic approach reverses nicotine dependence, decreases compulsive-like intake, and prevents relapse
A bacterial enzyme that eats nicotine reverses addiction-like behaviors and offers a new strategy to help smokers quit.
- Targeted delivery of antisense oligonucleotides to pancreatic β-cells
Receptor-dependent productive uptake of GLP1-conjugated antisense oligonucleotides occurs selectively in pancreatic β-cells.
- Switchable counterion gradients around charged metallic nanoparticles enable reception of radio waves
Stripping counterions from charged nanoparticles into a porous electrode enables current rectification at radio frequencies.
- Synthesis of stable and low-CO2 selective ε-iron carbide Fischer-Tropsch catalysts
Phase-pure ε-iron carbide catalysts amenable to scale-up exhibit low CO2 selectivity and high stability in the FT reaction.
- Wide-field multiphoton imaging through scattering media without correction
Focusing ultrashort laser pulses in time in tandem with single-pixel detection images at depth with no sample characterization.
- Uranium polyhydrides at moderate pressures: Prediction, synthesis, and expected superconductivity
Formation of uranium polyhydrides UH5–9 is predicted using the evolutionary algorithm USPEX and proved by high-pressure synthesis.
- A high-entropy alloy with hierarchical nanoprecipitates and ultrahigh strength
HEAs’ compositional space allows the design of hierarchical microstructures that contribute to the exceptional strength values.
- Shaping nanoparticle fingerprints at the interface of cholesteric droplets
Nanoparticles are organized into tunable, periodic patterns by controlling interfacial assembly with cholesteric liquid crystals.
About The Cover
COVER While the existence of exomoons—moons orbiting extrasolar planets—is probable, direct observational evidence of that existence has been elusive. Previous observations made using NASA's Kepler space telescope offered suggestions that Kepler-1625b, a Jupiter-sized planet orbiting the Solar-mass yellow star Kepler-1625, may be orbited by an exomoon. Now, Teachey and Kipping report additional observations made using the Hubble Space Telescope, as well as a refined analysis of Kepler photometry data, that strongly support the exomoon hypothesis. Their work suggests that this moon, if it exists, would be similar in size to Neptune or Uranus in our own Solar System. While the authors caution that their results must be confirmed by subsequent studies, the moon of Kepler-1625b ultimately could be the first confirmed exomoon. [CREDIT: DAN DURDA, FELLOW, INTERNATIONAL ASSOCIATION OF ASTRONOMICAL ARTISTS]