Research ArticleHEALTH AND MEDICINE

The matrikine N-α-PGP couples extracellular matrix fragmentation to endothelial permeability

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Science Advances  24 Apr 2015:
Vol. 1, no. 3, e1500175
DOI: 10.1126/sciadv.1500175

Article Information

vol. 1 no. 3

Online ISSN: 
History: 
  • Received for publication February 18, 2015
  • Accepted for publication February 25, 2015

Author Information

  1. Cornelia S. Hahn1,2,*,
  2. David W. Scott3,4,*,
  3. Xin Xu2,5,*,
  4. Mojtaba Abdul Roda2,6,
  5. Gregory A. Payne2,
  6. J. Michael Wells2,5,7,8,
  7. Liliana Viera2,5,
  8. Colleen J. Winstead4,
  9. Preston Bratcher2,5,
  10. Rolf W. Sparidans6,
  11. Frank A. Redegeld6,
  12. Patricia L. Jackson2,5,7,
  13. Gert Folkerts6,
  14. J. Edwin Blalock2,5,7,9,
  15. Rakesh P. Patel4,5, and
  16. Amit Gaggar2,5,7,8,9,,
  1. 1Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  2. 2Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
  3. 3Department of Cell Biology and Physiology, and Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  4. 4Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
  5. 5Program in Protease and Matrix Biology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
  6. 6Faculty of Science, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3508 TB Utrecht, Netherlands.
  7. 7Lung Health Center, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
  8. 8Medical Service at Birmingham VA Medical Center, Birmingham, AL 35233, USA.
  9. 9Department of Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
  1. Corresponding author. E-mail: agaggar1{at}uab.edu
    • * These authors contributed equally to this work.

    • These authors contributed equally to this work.

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