Research ArticleNANOMATERIALS

Functional droplets that recognize, collect, and transport debris on surfaces

+ See all authors and affiliations

Science Advances  28 Oct 2016:
Vol. 2, no. 10, e1601462
DOI: 10.1126/sciadv.1601462

You are currently viewing the abstract.

View Full Text

Abstract

We describe polymer-stabilized droplets capable of recognizing and picking up nanoparticles from substrates in experiments designed for transporting hydroxyapatite nanoparticles that represent the principal elemental composition of bone. Our experiments, which are inspired by cells that carry out materials transport in vivo, used oil-in-water droplets that traverse a nanoparticle-coated substrate driven by an imposed fluid flow. Nanoparticle capture is realized by interaction of the particles with chemical functionality embedded within the polymeric stabilizing layer on the droplets. Nanoparticle uptake efficiency is controlled by solution conditions and the extent of functionality available for contact with the nanoparticles. Moreover, in an elementary demonstration of nanoparticle transportation, particles retrieved initially from the substrate were later deposited “downstream,” illustrating a pickup and drop-off technique that represents a first step toward mimicking point-to-point transportation events conducted in living systems.

Keywords
  • Hydroxyapatite
  • emulsion droplet
  • catechol
  • phosphorylcholine
  • polydopamine

This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial license, which permits use, distribution, and reproduction in any medium, so long as the resultant use is not for commercial advantage and provided the original work is properly cited.

View Full Text

More Like This