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Research ArticleLIFE SCIENCES
A C9ORF72/SMCR8-containing complex regulates ULK1 and plays a dual role in autophagy
- Mei Yang1,*,
- Chen Liang1,*,
- Kunchithapadam Swaminathan2,
- Stephanie Herrlinger1,
- Fan Lai3,†,
- Ramin Shiekhattar3,† and
- Jian-Fu Chen1,†
- 1Department of Genetics and Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, USA.
- 2Department of Biological Sciences, National University of Singapore, 117543 Singapore.
- 3Department of Human Genetics, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
- ↵†Corresponding author. Email: chen2014{at}uga.edu (J.-F.C.); rshiekhattar{at}med.miami.edu (R.S.); FLai1{at}med.miami.edu (F.L.)
↵* These authors contributed equally to this work.
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Science Advances 02 Sep 2016:
Vol. 2, no. 9, e1601167
DOI: 10.1126/sciadv.1601167
Vol. 2, no. 9, e1601167
DOI: 10.1126/sciadv.1601167
Mei Yang
Department of Genetics and Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, USA.
Chen Liang
Department of Genetics and Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, USA.
Kunchithapadam Swaminathan
Department of Biological Sciences, National University of Singapore, 117543 Singapore.
Stephanie Herrlinger
Department of Genetics and Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, USA.
Fan Lai
Department of Human Genetics, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Ramin Shiekhattar
Department of Human Genetics, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Jian-Fu Chen
Department of Genetics and Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, USA.
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