Research ArticleGENETICS

CRISPR-Cpf1 correction of muscular dystrophy mutations in human cardiomyocytes and mice

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Science Advances  12 Apr 2017:
Vol. 3, no. 4, e1602814
DOI: 10.1126/sciadv.1602814

Article Information

vol. 3 no. 4

Online ISSN: 
History: 
  • Received for publication 13 November 2016.
  • Accepted for publication 14 February 2017.

Author Information

  1. Yu Zhang1,2,3,*,
  2. Chengzu Long1,2,3,*,,,
  3. Hui Li1,2,3,
  4. John R. McAnally1,2,3,
  5. Kedryn K. Baskin1,2,3,
  6. John M. Shelton4,
  7. Rhonda Bassel-Duby1,2,3 and
  8. Eric N. Olson1,2,3,
  1. 1Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  2. 2Senator Paul D. Wellstone Muscular Dystrophy Cooperative Research Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  3. 3Hamon Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  4. 4Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  1. Corresponding author. Email: Eric.Olson{at}UTSouthwestern.edu (E.N.O.); Chengzu.Long{at}nyumc.org (C.L.)
    • * These authors contributed equally to this work.

    • Present address: Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, NY 10016, USA.

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