Research ArticleGENETICS

The GH receptor exon 3 deletion is a marker of male-specific exceptional longevity associated with increased GH sensitivity and taller stature

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Science Advances  16 Jun 2017:
Vol. 3, no. 6, e1602025
DOI: 10.1126/sciadv.1602025

Article Information

vol. 3 no. 6

Online ISSN: 
History: 
  • Received for publication August 25, 2016
  • Accepted for publication April 26, 2017

Author Information

  1. Danny Ben-Avraham1,2,3,
  2. Diddahally R. Govindaraju3,4,
  3. Temuri Budagov1,3,
  4. Delphine Fradin5,
  5. Peter Durda6,
  6. Bing Liu7,
  7. Sandy Ott8,
  8. Danielle Gutman9,
  9. Lital Sharvit9,
  10. Robert Kaplan10,
  11. Pierre Bougnères5,11,
  12. Alex Reiner12,13,
  13. Alan R. Shuldiner8,14,
  14. Pinchas Cohen7,
  15. Nir Barzilai1,2,3 and
  16. Gil Atzmon1,2,3,9,*
  1. 1Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  2. 2Department of Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  3. 3Institute of Aging Research, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  4. 4Department of Human Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA.
  5. 5INSERM U986, Pincus Building, Bicêtre Hospital, Paris Sud University, 94275 Le Kremlin Bicêtre, France.
  6. 6Department of Pathology University of Vermont, 208 South Park Drive, Colchester, VT 05446, USA.
  7. 7Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA.
  8. 8University of Maryland School of Medicine, Baltimore, MD 21201, USA.
  9. 9Department of Human Biology, Faculty of Natural Sciences, University of Haifa, Haifa, Israel.
  10. 10Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  11. 11INSERM U1169 and Department of Pediatric Endocrinology and Diabetes, Bicêtre Hospital, Pôle I3E, Paris Sud University, 94275 Le Kremlin Bicêtre, France.
  12. 12Department of Epidemiology, University of Washington School of Public Health, Seattle, WA 98195, USA.
  13. 13Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  14. 14Geriatrics Research and Education Clinical Center, Veterans Administration Medical Center, Baltimore, MD 20420, USA.
  1. *Corresponding author. Email: gil.atzmon{at}einstein.yu.edu

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