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Serotonin rebalances cortical tuning and behavior linked to autism symptoms in 15q11-13 CNV mice

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Science Advances  21 Jun 2017:
Vol. 3, no. 6, e1603001
DOI: 10.1126/sciadv.1603001

Article Information

vol. 3 no. 6

Online ISSN: 
History: 
  • Received for publication November 30, 2016
  • Accepted for publication April 26, 2017

Author Information

  1. Nobuhiro Nakai1,2,3,*,
  2. Masatoshi Nagano4,*,
  3. Fumihito Saitow4,*,
  4. Yasuhito Watanabe2,5,,
  5. Yoshinobu Kawamura2,
  6. Akiko Kawamoto2,
  7. Kota Tamada1,2,
  8. Hiroshi Mizuma6,
  9. Hirotaka Onoe6,
  10. Yasuyoshi Watanabe6,
  11. Hiromu Monai1,
  12. Hajime Hirase1,
  13. Jin Nakatani7,
  14. Hirofumi Inagaki4,
  15. Tomoyuki Kawada4,
  16. Taisuke Miyazaki8,
  17. Masahiko Watanabe8,
  18. Yuka Sato9,
  19. Shigeo Okabe9,
  20. Kazuo Kitamura9,
  21. Masanobu Kano9,
  22. Kouichi Hashimoto2,
  23. Hidenori Suzuki4,10, and
  24. Toru Takumi1,2,10,
  1. 1RIKEN Brain Science Institute, Wako, Saitama 351-0198, Japan.
  2. 2Graduate School of Biomedical Sciences, Hiroshima University, Minami, Hiroshima 734-8553, Japan.
  3. 3Graduate School of Biostudies, Kyoto University, Sakyo, Kyoto 606-8501, Japan.
  4. 4Graduate School of Medicine, Nippon Medical School, Bunkyo, Tokyo 113-8602, Japan.
  5. 5Department of Clinical Neurobiology, University Hospital and German Cancer Research Center, Heidelberg 69120, Germany.
  6. 6RIKEN Center for Life Science Technologies, Chuo, Kobe 650-0047, Japan.
  7. 7Shiga University of Medical Science, Otsu, Shiga 520-2192, Japan.
  8. 8Department of Anatomy and Embryology, Hokkaido University Graduate School of Medicine, Kita, Sapporo 060-8638, Japan.
  9. 9Graduate School of Medicine, University of Tokyo, Bunkyo, Tokyo 113-8654, Japan.
  10. 10Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency, Tokyo, Japan.
  1. Corresponding author. Email: toru.takumi{at}riken.jp (T.T.); hsuzuki{at}nms.ac.jp (H.S.); y.watanabe{at}dkfz-heidelberg.de (Yasuhito Watanabe)
    • * These authors contributed equally to this work.

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