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Identifying the substrate proteins of U-box E3s E4B and CHIP by orthogonal ubiquitin transfer

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Science Advances  03 Jan 2018:
Vol. 4, no. 1, e1701393
DOI: 10.1126/sciadv.1701393

Article Information

vol. 4 no. 1

Online ISSN: 
History: 
  • Received for publication April 30, 2017
  • Accepted for publication December 1, 2017

Author Information

  1. Karan Bhuripanyo1,2,*,
  2. Yiyang Wang1,*,
  3. Xianpeng Liu3,*,
  4. Li Zhou1,
  5. Ruochuan Liu1,
  6. Duc Duong4,
  7. Bo Zhao5,
  8. Yingtao Bi6,
  9. Han Zhou1,
  10. Geng Chen1,
  11. Nicholas T. Seyfried7,
  12. Walter J. Chazin8,
  13. Hiroaki Kiyokawa3, and
  14. Jun Yin1,
  1. 1Department of Chemistry, Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30303, USA.
  2. 2Department of Chemistry, University of Chicago, Chicago, IL 60637, USA.
  3. 3Department of Pharmacology, Northwestern University, Chicago, IL 60611, USA.
  4. 4Integrated Proteomics Core, Emory University, Atlanta, GA 30322, USA.
  5. 5Engineering Research Center of Cell and Therapeutic Antibody, Ministry of Education, and School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China.
  6. 6AbbVie Bioresearch Center, Worcester, MA 01605, USA.
  7. 7Department of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322, USA.
  8. 8Departments of Biochemistry and Chemistry, Center for Structural Biology, Vanderbilt University, Nashville, TN 37232, USA.
  1. Corresponding author. Email: junyin{at}gsu.edu (J.Y.); kiyokawa{at}northwestern.edu (H.K.)
    • * These authors contributed equally to this work.

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