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Stereochemistry and amyloid inhibition: Asymmetric triplex metallohelices enantioselectively bind to Aβ peptide

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Science Advances  19 Jan 2018:
Vol. 4, no. 1, eaao6718
DOI: 10.1126/sciadv.aao6718

Article Information

vol. 4 no. 1

Online ISSN: 
History: 
  • Received for publication August 14, 2017
  • Accepted for publication December 11, 2017

Author Information

  1. Yijia Guan1,2,
  2. Zhi Du1,2,
  3. Nan Gao1,
  4. Yue Cao1,
  5. Xiaohui Wang1,
  6. Peter Scott3,
  7. Hualong Song3,
  8. Jinsong Ren1 and
  9. Xiaogang Qu1,*
  1. 1Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China.
  2. 2University of Chinese Academy of Sciences, Beijing 100039, China.
  3. 3Department of Chemistry, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK.
  1. *Corresponding author. Email: xqu{at}ciac.ac.cn

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