Research ArticleGENETICS

Correction of diverse muscular dystrophy mutations in human engineered heart muscle by single-site genome editing

See allHide authors and affiliations

Science Advances  31 Jan 2018:
Vol. 4, no. 1, eaap9004
DOI: 10.1126/sciadv.aap9004

Article Information

vol. 4 no. 1

Online ISSN: 
History: 
  • Received for publication September 7, 2017
  • Accepted for publication December 28, 2017

Author Information

  1. Chengzu Long1,2,3,4,*,,
  2. Hui Li1,2,3,*,
  3. Malte Tiburcy5,6,
  4. Cristina Rodriguez-Caycedo1,2,3,
  5. Viktoriia Kyrychenko1,2,3,
  6. Huanyu Zhou1,2,3,
  7. Yu Zhang1,2,3,
  8. Yi-Li Min1,2,3,
  9. John M. Shelton7,
  10. Pradeep P. A. Mammen2,3,7,
  11. Norman Y. Liaw5,
  12. Wolfram-Hubertus Zimmermann5,6,
  13. Rhonda Bassel-Duby1,2,3,
  14. Jay W. Schneider2,3,7 and
  15. Eric N. Olson1,2,3,
  1. 1Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  2. 2Senator Paul D. Wellstone Muscular Dystrophy Cooperative Research Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  3. 3Hamon Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  4. 4Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, NY 10016, USA.
  5. 5Institute of Pharmacology and Toxicology, University Medical Center, Georg-August-University Göttingen, Göttingen, 37075, Germany.
  6. 6DZHK (German Center for Cardiovascular Research), partner site Göttingen, Göttingen, Germany.
  7. 7Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  1. Corresponding author. Email: eric.olson{at}utsouthwestern.edu (E.N.O.); chengzu.long{at}nyumc.org (C.L.)
    • * These authors contributed equally to this work.

    Altmetric

    Article usage

    Article usage: January 2018 to December 2018

    AbstractFullPdf
    Jan 2018794537184
    Feb 20181022547794520
    Mar 20181045734672
    Apr 2018659666512
    May 2018539716464
    Jun 2018412489242
    Jul 2018245693179
    Aug 20186812255
    Sep 201801085276
    Oct 20184891165
    Nov 20180827214
    Dec 20180360128

    Navigate This Article