Research ArticleVIROLOGY

HIV-1 vaccine design through minimizing envelope metastability

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Science Advances  21 Nov 2018:
Vol. 4, no. 11, eaau6769
DOI: 10.1126/sciadv.aau6769

Article Information

vol. 4 no. 11

Online ISSN: 
History: 
  • Received for publication July 6, 2018
  • Accepted for publication October 19, 2018

Author Information

  1. Linling He1,*,
  2. Sonu Kumar2,3,4,*,
  3. Joel D. Allen5,
  4. Deli Huang1,
  5. Xiaohe Lin1,
  6. Colin J. Mann1,
  7. Karen L. Saye-Francisco4,
  8. Jeffrey Copps2,4,
  9. Anita Sarkar2,3,4,
  10. Gabrielle S. Blizard1,
  11. Gabriel Ozorowski2,3,4,
  12. Devin Sok2,3,4,
  13. Max Crispin5,
  14. Andrew B. Ward2,3,4,
  15. David Nemazee1,
  16. Dennis R. Burton1,3,4,6,
  17. Ian A. Wilson2,3,4,7, and
  18. Jiang Zhu1,2,
  1. 1Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  2. 2Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  3. 3International AIDS Vaccine Initiative Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA.
  4. 4Scripps Center for HIV/AIDS Vaccine Immunology & Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA.
  5. 5Centre for Biological Sciences and Institute for Life Sciences, University of Southampton, Highfield Campus, Southampton SO17 1BJ, UK.
  6. 6Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard, Cambridge, MA 02139-3583, USA.
  7. 7Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  1. Corresponding author. Email: wilson{at}scripps.edu (I.A.W.); jiang{at}scripps.edu (J.Z.)
  • * These authors contributed equally to this work.

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