Porphyromonas gingivalis in Alzheimer’s disease brains: Evidence for disease causation and treatment with small-molecule inhibitors

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Science Advances  23 Jan 2019:
Vol. 5, no. 1, eaau3333
DOI: 10.1126/sciadv.aau3333

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  • RE: Further research on microbes in Alzheimer's disease
    • Leslie C. Norins, Founder and CEO, Alzheimer's Germ Quest, Inc. (

    This stimulating contribution is a welcome addition to the renaissance of research interest in infectious agents that can trigger or promote Alzheimer's disease. Unfortunately, the U.S. government's designated principal funder of Alzheimer's research, the National Institute on Aging, has so far given little encouragement and only paltry funding to such investigations. Congress's current record appropriation of $2.3 billion for NIH Alzheimer's research provides the NIA ample opportunity to make up for lost time and opportunity.

    Leslie C.Norins, MD, PhD
    Founder and CEO
    Alzheimer's Germ Quest, Inc.
    (An independent, self-funded public benefit corporation which neither solicits nor accepts outside donations or grants)
    4301 Gulfshore Blvd., Suite 1404
    Naples, FL 34103

    Competing Interests: None declared.

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