Science Advances

Supplementary Materials

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  • Fig. S1. MD, serum cortisol levels, and timing of awakenings are similar across groups and magnitude of RSD effect comparable to pharmacological block of plasticity.
  • Fig. S2. Single-unit recordings in V1 confirm the results from optical imaging.
  • Fig. S3. RSD decreases cofilin levels, but not GluA1 phosphorylation, in V1.
  • Fig. S4. RSD reduces ERK phosphorylation in nonvisual brain regions.
  • Fig. S5. REM sleep in the first 2 hours after MD rescues and protects ODP from further disruption.
  • Fig. S6. REM sleep is selectively reduced in the 2 hours after MD.
  • Fig. S7. ERK phosphorylation is normal in the RSD + recovery and delayed RSD groups.
  • Fig. S8. EEG activity in REM sleep correlates with ODP and ERK phosphorylation.
  • Table S1. Numbers and ages of animals used in the 1-hour groups.
  • Table S2. Numbers and ages of animals used in the 2-hour groups.
  • Table S3. Training and cross-validation of an ANN using the MLP architecture.
  • Table S4. Testing and performance of an ANN using the MLP architecture.

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