Science Advances

Supplementary Materials

This PDF file includes:

  • fig. S1. Growth curve and independent replicates of life-span analysis in yeast.
  • fig. S2. Replicative life span in yeast experiment.
  • fig. S3. Gompertz fits of survival curves in different experiments.
  • fig. S4. Age-associated changes in amino acid levels in fruitflies.
  • fig. S5. Change of body weights and life span of the control group compared with the young and old diet groups in mice.
  • fig. S6. Percentage of mice with tumor and tumor spectrum in the different diet groups.
  • fig. S7. Fecal microbiota of female mice at 270 days after starting the diet.
  • table S1. Replicative life-span analysis of yeast cells grown on young and old diets.
  • table S2. Life-span analysis from survival curves in the young and old diet groups in fruitflies.
  • table S3. Proximate composition (%, w/w) of muscles from young and old red deer.
  • table S4. Ingredients, energy, and macronutrient content of experimental diets in the mice study.
  • table S5. Life-span analysis from survival curves in the young and old dietary groups in mice.
  • table S6. Life-span analysis from survival curves of the control group compared with the young and old diet groups.
  • table S7. Pathology at time of death in all experimental diet groups.
  • Legend for table S8

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Other Supplementary Material for this manuscript includes the following:

  • table S8 (Microsoft Excel format). Relative abundance of selected bacterial groups found in fecal samples of female mice.

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