Science Advances

Supplementary Materials

This PDF file includes:

  • Supplementary Text
  • fig. S1. Optical camera images of the wearable diabetes patch.
  • fig. S2. Device fabrication process.
  • fig. S3. Schematic illustration of the operation sequence of the diabetes treatment system.
  • fig. S4. Electrochemical analysis of the planar and porous gold electrode.
  • fig. S5. Drug delivery from microneedles with integrated heaters.
  • fig. S6. Effect of the sweat control layers and miniaturization of the glucose sensor.
  • fig. S7. Characterization of the glucose sensor.
  • fig. S8. Characterization of the pH sensor.
  • fig. S9. Skin temperature and characterization of chlorpropamide-loaded PCNs.
  • fig. S10. Characterization of hyaluronic acid, DOPA-conjugated hyaluronic acid.
  • fig. S11. Characterization of the PCNs.
  • fig. S12. Fabrication process of the microneedles.
  • fig. S13. Characterization of the heater and temperature sensor and their cooperation.
  • fig. S14. Portable electrochemical analyzer for the wearable diabetes patch.
  • fig. S15. Reliability of the wearable diabetes patch under variable skin temperature and multiple reuses.
  • fig. S16. Sweat uptake and calibration of the disposable strip-type sensors.
  • fig. S17. Human sweat analysis.
  • fig. S18. Feedback microneedle therapy.

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