Science Advances

Supplementary Materials

This PDF file includes:

  • fig. S1. Generation of myeloid lineage-specific conditional IPMK-null mice.
  • fig. S2. Validation of myeloid lineage-specific conditional IPMK-null mice.
  • fig. S3. IPMK depletion in macrophages blunts TLR-dependent inflammatory responses.
  • fig. S4. IPMK depletion in RAW 264.7 macrophages down-regulates TLR-dependent inflammatory responses.
  • fig. S5. IPMK depletion in macrophages does not alter TLR3-dependent inflammatory responses.
  • fig. S6. Upstream TLR signaling regulators are not altered in IPMK-depleted macrophages.
  • fig. S7. Overexpression of IPMK reduces TRAF6 ubiquitination.

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