Science Advances

Supplementary Materials

The PDF file includes:

  • Fig. S1. Schematic of the experimental scheme used to confirm the movement of the propellers in the vitreous.
  • Fig. S2. Intravitreal propulsion of micropropellers with different coatings.
  • Fig. S3. SEM images of the micropropellers grown with TiO2 and Fe.
  • Fig. S4. Time-lapse images showing the controlled movement (forward/backward) of the slippery Fe-containing propellers when actuated by the external magnetic field.
  • Fig. S5. Percentage of propelling micropropellers containing Ni (black) and those made with Fe (red) in vitreous with different surface coatings.
  • Fig. S6. Percentage of propelling slippery propellers in vitreous before and after incubation within 5% bovine serum albumin in PBS solution for 2 hours.
  • Fig. S7. Characterization of the surface coating on the micropropellers by AFM.
  • Fig. S8. Intravitreal propulsion of the slippery propellers as a function of the magnetic field strength.
  • Fig. S9. Propulsion of the slippery micropropellers in glycerol solution.
  • Fig. S10. Fluorescence images of the excised retina.
  • Fig. S11. Investigation of the distribution of the propellers on the retina.
  • Fig. S12. The M-H curve of a wafer piece (area of 10 mm2) containing an array of microhelices.
  • Table S1. Statistical analysis of micropropellers moving in vitreous as a function of the surface coating.
  • Legends for movies S1 to S5

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Other Supplementary Material for this manuscript includes the following:

  • Movie S1 (.avi format). Wobbling motion of an uncoated micropropeller in the vitreous under the actuation of a rotating magnetic field with a strength of 8 mT and a frequency of 6 Hz.
  • Movie S2 (.avi format). Propulsion of a slippery micropropeller in the vitreous under the actuation of a rotating magnetic field with a strength of 8 mT and a frequency of 6 Hz.
  • Movie S3 (.avi format). A large swarm of slippery micropropellers moves across the boundary of an aqueous buffer into the vitreous and continues propelling in the vitreous under a rotating magnetic field with a strength of 8 mT and a frequency of 70 Hz.
  • Movie S4 (.avi format). Controlled motion of slippery micropropellers in the vitreous under a rotating magnetic field with a strength of 8 mT and a frequency of 50 Hz.
  • Movie S5 (.avi format). OCT shows the distribution of the slippery micropropellers at the vitreous-retina boundary.

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