- Unraveling structures of protection ligands on gold nanoparticle Au68(SH)32
A divide and protect approach to unraveling the atomic structure of a thiolate-protected gold nanoparticle.
- Abacavir, an anti–HIV-1 drug, targets TDP1-deficient adult T cell leukemia
An anti–HIV-1 drug is found to destroy leukemia cells in adults.
- The microbiome of uncontacted Amerindians
Fecal, oral, and skin biomes of isolated Amerindians show higher human bacterial diversity including antibiotic resistance genes.
- Growth of asteroids, planetary embryos, and Kuiper belt objects by chondrule accretion
Chondrules, tiny spheres found in primitive meteorites, accumulate through gas drag to form asteroids and planetary embryos.
- Optimized unconventional superconductivity in a molecular Jahn-Teller metal
A superconductivity dome is created by the electronic structure of the molecular building block of an unconventional superconductor.
- Experimental scattershot boson sampling
A novel experiment supports quantum computation using photonic circuits to greatly increase quantum device speed.
- Crowdsourced earthquake early warning
Consumer devices and real and simulated earthquake data demonstrate that earthquake early warning can be achieved via crowdsourcing.
- Electrically controlling single-spin qubits in a continuous microwave field
Control of individual spin qubits through local electric fields, suitable for large-scale silicon quantum computers.
- PlGF-induced VEGFR1-dependent vascular remodeling determines opposing antitumor effects and drug resistance to Dll4-Notch inhibitors
Notch inhibitors cause cancer growth in tumors expressing PIGFβ protein.
- Specific activation of the TLR1-TLR2 heterodimer by small-molecule agonists
A small-molecule agonist of the Toll-like receptor 1/2 signaling pathway does it by stabilizing heterodimeric associations.
- A Candida albicans CRISPR system permits genetic engineering of essential genes and gene families
CRISPR simplifies genetic engineering of the human fungal pathogen Candida albicans.
- Inhibiting macrophage proliferation suppresses atherosclerotic plaque inflammation
Nanoparticle-based delivery of simvastatin inhibits plaque macrophage proliferation in apolipoprotein E–deficient mice.
- Life and death of a single catalytic cracking particle
Macropore blocking through metal deposition and intrusion of particles is a major deactivation mechanism in FCC catalysts essential to gasoline production.
- By-product metals are technologically essential but have problematic supply
Metals that are obtained largely or entirely as by-products are essential to modern technology, but their supplies may be constrained due to a variety of factors.
About The Cover
ONLINE COVER Phosphorescence—which, unlike fluorescence, involves reemission of light on a slower timescale—is used in glow-in-the-dark products, including illuminating emergency signs. It is also used for information storage purposes such as stamp detection. Easier and less expensive fabrication methods for phosphorescence systems have been created via organic emitters but achieving visible organic phosphorescence under ambient conditions remains challenging. In a new study, Gmelch et al. report a "new milestone" in organic luminescent labeling. They used a simple device structure made of highly available materials, through which ultrathin, flexible and transparent luminescent coatings could be generated. Their labeling device is fast and capable of printing more than 40 cycles of information onto any substrate of any size at high resolution (more than 700 dpi). Using light alone, any luminescent image can be printed and erased without the need of ink, via their approach. This concept say Gmelch et al., represents a way to produce luminescent on-demand tags and is a promising replacement for conventional labeling techniques. [CREDIT: MAX GMELCH AND HEIDI THOMAS/TECHNISCHE UNIVERSITÄT DRESDEN (TUD)]