• Global patterns and drivers of ecosystem functioning in rivers and riparian zones

    An experiment in >1000 river and riparian sites found spatial patterns and controls of carbon processing at the global scale.

  • Iron is neurotoxic in retinal detachment and transferrin confers neuroprotection

    Ocular fluids from patients with retinal detachment show iron accumulation, and transferrin can be used as a therapeutic adjuvant.

  • Cofilin hyperactivation in HIV infection and targeting the cofilin pathway using an anti-α4β7 integrin antibody

    We demonstrate an HIV-mediated dysregulation of cofilin in CD4 T cells and propose therapeutics to restore T cell motility.

  1. « 1
  2. ‹ previous
  3. 1
  4. 2
  5. 3
  6. 4
  7. 5
  8. next ›
  9. 179 »

About The Cover

Cover image expansion

ONLINE COVER To determine how North Africa's climate has evolved over the past millions of years, experts have studied dust flux records from marine sediments. These long-term records are based largely on fluxes calculated using age model-based mass accumulation rates (MARs). However, this method suffers from many potential biases, including limited resolution. The paleoclimate community has recently diverted from the MAR approach and has started to use constant flux proxies, such as excess 230Th from seawater that can be used to determine sediment accumulation rates. Relying on 230Th from marine sediment cores to more reliably calculate fluxes, Skonieczny et al. present the first Saharan dust record than spans many glacial cycles. They discovered that in the Sahara Desert, dust emissions over the last 240,000 years have varied in accordance with Northern Hemisphere summer monsoons rather than glacial-interglacial changes as had been previously assumed. These results question the use of existing Pleistocene dust records to examine the connections between climate and hominid evolution. CREDIT: GIDEON MENDEL/CORBIS VIA GETTY IMAGES