Table 4 FSFs shared by different viral subgroups.
SCOP IDSCOP cssFSF descriptionDistribution
56672e.8.1DNA/RNA polymerasesdsDNA, dsRNA, dsDNA-RT, ssRNA-RT, minus-ssRNA, plus-ssRNA
52540c.37.1P-loop containing nucleoside triphosphate hydrolasesdsDNA, dsRNA, ssDNA, plus-ssRNA
53335c.66.1S-Adenosyl-l-methionine–dependent methyltransferasesdsDNA, dsRNA, ssDNA, minus-ssRNA, plus-ssRNA
53098c.55.3Ribonuclease H–likedsDNA, ssRNA-RT, ssDNA, minus-ssRNA
88633b.121.4Positive stranded ssRNA virusesdsDNA, dsRNA, minus-ssRNA, plus-ssRNA
57850g.44.1RING/U-boxdsDNA, minus-ssRNA, plus-ssRNA
51283b.85.4dUTPase-likedsDNA, dsDNA-RT, ssRNA-RT
56112d.144.1Protein kinase–like (PK-like)dsDNA, dsRNA, ssRNA-RT
54768d.50.1dsRNA binding domain–likedsDNA, dsRNA, plus-ssRNA
54001d.3.1Cysteine proteinasesdsDNA, minus-ssRNA, plus-ssRNA
52266c.23.10SGNH hydrolasedsDNA, minus-ssRNA, plus-ssRNA
58100h.4.4Bacterial hemolysinsdsDNA, dsRNA, ssDNA
49818b.19.1Viral protein domaindsRNA, minus-ssRNA, plus-ssRNA
57756g.40.1Retrovirus zinc finger–like domainsdsDNA, dsDNA-RT, ssRNA-RT
50044b.34.2SH3 domaindsDNA, dsRNA, ssRNA-RT
57924g.52.1Inhibitor of apoptosis (IAP) repeatdsDNA, plus-ssRNA
50249b.40.4Nucleic acid binding proteinsdsDNA, ssDNA
53041c.53.1Resolvase-likedsDNA, ssDNA
55550d.93.1SH2 domaindsDNA, ssRNA-RT
55464d.89.1Origin of replication binding domain, RBD-likedsDNA, ssDNA
56399d.166.1ADP ribosylationdsDNA, ssDNA
100920b.130.1Heat shock protein 70 kD (HSP70), peptide binding domaindsDNA, plus-ssRNA
47413a.35.1Lambda repressor–like DNA binding domainsdsDNA, ssDNA
69065a.149.1RNase III domain–likedsDNA, plus-ssRNA
46785a.4.5Winged helix DNA binding domaindsDNA, ssDNA
53448c.68.1Nucleotide-diphospho-sugar transferasesdsDNA, dsRNA
57997h.1.5TropomyosindsDNA, dsRNA
54236d.15.1Ubiquitin-likedsDNA, ssRNA-RT
47954a.74.1Cyclin-likedsDNA, ssRNA-RT
90229g.66.1CCCH zinc fingerdsDNA, minus-ssRNA
103657a.238.1BAR/IMD domain–likedsDNA, ssRNA-RT
53067c.55.1Actin-like ATPase domaindsDNA, plus-ssRNA
47794a.60.4Rad51 N-terminal domain–likedsDNA, ssDNA
143990d.336.1YbiA-likedsDNA, plus-ssRNA
55811d.113.1NudixdsDNA, dsRNA
51197b.82.2Clavaminate synthase–likedsDNA, plus-ssRNA
53756c.87.1UDP-glycosyltransferase/glycogen phosphorylasedsDNA, dsRNA
81665f.33.1Calcium ATPase, transmembrane domain MdsDNA, plus-ssRNA
52949c.50.1Macro domain–likedsDNA, plus-ssRNA
53955d.2.1Lysozyme-likedsDNA, dsRNA
49899b.29.1Concanavalin A–like lectins/glucanasesdsDNA, dsRNA
48371a.118.1ARM repeatdsDNA, plus-ssRNA
51126b.80.1Pectin lyase–likedsDNA, plus-ssRNA
47598a.43.1Ribbon-helix-helixdsDNA, ssDNA
50494b.47.1Trypsin-like serine proteasesdsDNA, plus-ssRNA
55144d.61.1LigT-likedsDNA, plus-ssRNA
81296b.1.18E set domainsdsDNA, plus-ssRNA
161008e.76.1Viral glycoprotein ectodomain–likedsDNA, minus-ssRNA
90257h.1.26Myosin rod fragmentsdsDNA, dsRNA
57501g.17.1Cystine-knot cytokinesdsDNA, ssRNA-RT
54117d.9.1Interleukin 8–like chemokinesdsDNA, dsRNA
58069h.3.2Virus ectodomainssRNA-RT, minus-ssRNA
50630b.50.1Acid proteasesdsDNA-RT, ssRNA-RT
47459a.38.1HLH, helix-loop-helix DNA binding domaindsDNA, ssRNA-RT
50939b.68.1SialidasesdsDNA, minus-ssRNA
55166d.65.1Hedgehog/DD peptidasedsDNA, ssDNA
51225b.83.1Fiber shaft of virus attachment proteinsdsDNA, dsRNA
49835b.21.1Virus attachment protein globular domaindsDNA, dsRNA
111474h.3.3Coronavirus S2 glycoproteindsDNA, plus-ssRNA
55658d.100.1L9 N-domain–likedsDNA, dsDNA-RT
55895d.124.1Ribonuclease Rh–likedsDNA, plus-ssRNA
52972c.51.4ITPase-likedsDNA, plus-ssRNA
57959h.1.3Leucine zipper domaindsDNA, ssRNA-RT
50203b.40.2Bacterial enterotoxinsdsDNA, ssDNA
48208a.102.1Six-hairpin glycosidasesdsDNA, ssDNA
50022b.33.1ISP domaindsDNA, ssRNA-RT
58064h.3.1Influenza hemagglutinin (stalk)dsDNA, minus-ssRNA