- A Global Deal For Nature: Guiding principles, milestones, and targets
The Global Deal for Nature sets an ambitious agenda to protect our biosphere through ecosystem conservation and land restoration.
- Climbing-inspired twining electrodes using shape memory for peripheral nerve stimulation and recording
Proposed 3D neural electrode can self-climb onto peripheral nerve driven by body temperature and form flexible neural interface.
- Dual-gradient enabled ultrafast biomimetic snapping of hydrogel materials
We present a new paradigm for designing responsive hydrogel sheets that can exhibit ultrafast snapping deformation.
- Energy renormalization for coarse-graining polymers having different segmental structures
We provide a computational test of the energy renormalization method to coarse-grain polymers with different segmental structures.
- Origin of giant negative piezoelectricity in a layered van der Waals ferroelectric
Lattice topology and anisotropic chemical bonds underpin unusual negative longitudinal piezoelectricity in van der Waals solids.
- A polyaromatic receptor with high androgen affinity
A synthetic model of androgen bioreceptors strictly discriminates male hormones from female ones in its polyaromatic cavity.
- Combinatorial optimization by simulating adiabatic bifurcations in nonlinear Hamiltonian systems
Nonlinear Hamiltonian systems search optimal solutions exploiting their adiabatic and chaotic evolutions.
- Room temperature polariton lasing in quantum heterostructure nanocavities
A room temperature polariton nanolaser is demonstrated using quantum heterostructure nanocavities to boost exciton properties.
- Direct observation of valley-coupled topological current in MoS2
Electrical generation and detection of valley currents in MoS2 is demonstrated as a robust phenomenon even at room temperature.
- Heat flowing from cold to hot without external intervention by using a “thermal inductor”
We show that heat can flow from cold to hot using a thermal inductor, without violating the second law of thermodynamics.
- Autonomous microfluidic actuators for periodic sequential flow generation
We report a microfluidic system that generates sequential periodic multiflows only with a constant water head pressure.
- Olanzapine: A potent agonist at the hM4D(Gi) DREADD amenable to clinical translation of chemogenetics
The atypical antipsychotic olanzapine is a potent activator of a mutated muscarinic receptor used for chemogenetic inhibition.
- Urine salts elucidate Early Neolithic animal management at Aşıklı Höyük, Turkey
Soluble salts in archaeological sediments reveal an increasing scale of caprine management at Aşıklı Höyük, Turkey.
- Critical role of spectrin in hearing development and deafness
Super-resolution fluorescence imaging reveals a previously unknown novel structure of spectrin in inner ear hair cells.
About The Cover
ONLINE COVER Though the River Nile supports millions of human livelihoods and holds globally important fish biodiversity, it remains under-protected. No basin-wide spatial conservation planning has been attempted to date. Here, Allan et al. put forward a basin-wide conservation prioritization approach. They compare different cross-boundary collaboration scenarios for achieving biodiversity conservation targets, finding that collaborative conservation efforts are crucial for reducing conservation costs—resulting in a 34% savings compared to uncoordinated, business-as-usual scenarios. The researchers also identify priority areas for conservation action. Conservation priority "hotspots" that were consistently selected across all the collaboration scenarios include the Nile Delta in Egypt, Northern Sudan and Southern Egypt, and the East African Great Lakes. The researchers' approach represents a framework for improving conservation at large and complex river systems globally. [CREDIT: J.D. DALLET/AGE FOTOSTOCK/ALAMY STOCK PHOTO]