- Evolution of metabolic novelty: A trichome-expressed invertase creates specialized metabolic diversity in wild tomato
Evolution of a cell specific invertase enzyme creates phenotypic diversity in wild tomato insecticidal metabolite production.
- Who hit the ball out? An egocentric temporal order bias
Self-generated action events are perceived to occur before external events, leading to differences in subjective temporal order.
- Persistent Early to Middle Holocene tropical foraging in southwestern Amazonia
Archaeological research indicates that hunter-gatherers altered landscapes in southwestern Amazonia as early as 10,000 years ago.
- Clean air for some: Unintended spillover effects of regional air pollution policies
Improving air quality can come at the cost of increasing emissions and environmental deterioration elsewhere.
- The protein kinase activity of fructokinase A specifies the antioxidant responses of tumor cells by phosphorylating p62
KHK-A, a metabolic enzyme in fructose metabolism, acts as a protein kinase to phosphorylate p62 for tumor antioxidant responses.
- Exceptional preservation of mid-Cretaceous marine arthropods and the evolution of novel forms via heterochrony
A “beautiful chimera” from the mid-Cretaceous sheds light on the evolution of novel forms and forces a rethink of what a crab is.
- Quantifying landslide frequency and sediment residence time in the Nepal Himalaya
The record of landslide erosion in river sand reveals that sediment resides in steep mountains for no more than tens of years.
- Rehearsal initiates systems memory consolidation, sleep makes it last
Rehearsal shifts mnemonic processing from the hippocampus to the posterior parietal cortex, sleep stabilizes the transition.
- An aerobic eukaryotic parasite with functional mitochondria that likely lacks a mitochondrial genome
The parasitic marine dinoflagellate Amoebophrya is the first known eukaryote with aerobic mitochondria without a genome.
- RUNX represses Pmp22 to drive neurofibromagenesis
RUNX 1 and RUNX3 drive Nf1 neurofibromagenesis by mediating the promoter usage and inducing levels of protein expression of PMP22.
- PRC2 recruitment and H3K27me3 deposition at FLC require FCA binding of COOLAIR
H3K27me3 deposition at FLC requires FCA-COOLAIR binding; SSU72 antagonizes this binding, thus reducing H3K27me3 deposition at FLC.
- Focal infrared neural stimulation with high-field functional MRI: A rapid way to map mesoscale brain connectomes
We have developed INS-fMRI as a rapid and high-resolution method for mapping functional brain networks in vivo.
- Ice-stream demise dynamically conditioned by trough shape and bed strength
We show how the shape and strength of an ice stream’s bed can drive step changes in retreat rate and hasten ice loss to the ocean.
- When males live longer: Resource-driven territorial behavior drives sex-specific survival in snakes
Egg-defending females die earlier than males, demonstrating the cost of territoriality.
About The Cover
ONLINE COVER Though the River Nile supports millions of human livelihoods and holds globally important fish biodiversity, it remains under-protected. No basin-wide spatial conservation planning has been attempted to date. Here, Allan et al. put forward a basin-wide conservation prioritization approach. They compare different cross-boundary collaboration scenarios for achieving biodiversity conservation targets, finding that collaborative conservation efforts are crucial for reducing conservation costs—resulting in a 34% savings compared to uncoordinated, business-as-usual scenarios. The researchers also identify priority areas for conservation action. Conservation priority "hotspots" that were consistently selected across all the collaboration scenarios include the Nile Delta in Egypt, Northern Sudan and Southern Egypt, and the East African Great Lakes. The researchers' approach represents a framework for improving conservation at large and complex river systems globally. [CREDIT: J.D. DALLET/AGE FOTOSTOCK/ALAMY STOCK PHOTO]