Research ArticleBIOPHYSICS

Myosin-binding protein C corrects an intrinsic inhomogeneity in cardiac excitation-contraction coupling

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Science Advances  20 Feb 2015:
Vol. 1, no. 1, e1400205
DOI: 10.1126/sciadv.1400205

Article Information

vol. 1 no. 1

Online ISSN: 
History: 
  • Received for publication December 12, 2014
  • Accepted for publication January 4, 2015

Author Information

  1. Michael J. Previs1,*,
  2. Benjamin L. Prosser2,*,
  3. Ji Young Mun3,4,*,
  4. Samantha Beck Previs1,
  5. James Gulick5,
  6. Kyounghwan Lee3,
  7. Jeffrey Robbins5,
  8. Roger Craig3,,
  9. W. J. Lederer6, and
  10. David M. Warshaw1,
  1. 1Department of Molecular Physiology and Biophysics, Cardiovascular Research Institute of Vermont, The University of Vermont, Burlington, VT 05405, USA.
  2. 2Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  3. 3Department of Cell and Developmental Biology, University of Massachusetts Medical School, Worcester, MA 01655, USA.
  4. 4Department of Biomedical Laboratory Science, College of Health Sciences, Eulji University, Seongnam-Si 461-701, Gyeonggi-Do, Republic of Korea.
  5. 5Department of Pediatrics and the Heart Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229, USA.
  6. 6Department of Physiology, Center for Biomedical Engineering and Technology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
  1. Corresponding author. E-mail: david.warshaw{at}uvm.edu (D.M.W.); jlederer{at}umaryland.edu (W.J.L.); roger.craig{at}umassmed.edu (R.C.)
  • * These authors contributed equally to this work.

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