Research ArticlePHARMACOLOGY
Specific activation of the TLR1-TLR2 heterodimer by small-molecule agonists
- Kui Cheng1,
- Meng Gao1,
- James I. Godfroy2,
- Peter N. Brown2,
- Noah Kastelowitz2 and
- View ORCID ProfileHang Yin1,2,*
- 1Center of Basic Molecular Science, Department of Chemistry, Tsinghua University, Beijing 100082, China.
- 2Department of Chemistry and Biochemistry and the BioFrontiers Institute, University of Colorado Boulder, Boulder, CO 80309, USA.
- ↵*Corresponding author. E-mail: hang.yin{at}colorado.edu
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Science Advances 10 Apr 2015:
Vol. 1, no. 3, e1400139
DOI: 10.1126/sciadv.1400139
Vol. 1, no. 3, e1400139
DOI: 10.1126/sciadv.1400139
Kui Cheng
1Center of Basic Molecular Science, Department of Chemistry, Tsinghua University, Beijing 100082, China.
Meng Gao
1Center of Basic Molecular Science, Department of Chemistry, Tsinghua University, Beijing 100082, China.
James I. Godfroy
2Department of Chemistry and Biochemistry and the BioFrontiers Institute, University of Colorado Boulder, Boulder, CO 80309, USA.
Peter N. Brown
2Department of Chemistry and Biochemistry and the BioFrontiers Institute, University of Colorado Boulder, Boulder, CO 80309, USA.
Noah Kastelowitz
2Department of Chemistry and Biochemistry and the BioFrontiers Institute, University of Colorado Boulder, Boulder, CO 80309, USA.
Hang Yin
1Center of Basic Molecular Science, Department of Chemistry, Tsinghua University, Beijing 100082, China.
2Department of Chemistry and Biochemistry and the BioFrontiers Institute, University of Colorado Boulder, Boulder, CO 80309, USA.
