Research ArticleHEALTH AND MEDICINE

Screening system for drug-induced arrhythmogenic risk combining a patch clamp and heart simulator

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Science Advances  01 May 2015:
Vol. 1, no. 4, e1400142
DOI: 10.1126/sciadv.1400142

Article Information

vol. 1 no. 4

Online ISSN: 
History: 
  • Received for publication November 25, 2014
  • Accepted for publication April 4, 2015

Author Information

  1. Jun-ichi Okada1,2,*,
  2. Takashi Yoshinaga3,
  3. Junko Kurokawa4,
  4. Takumi Washio1,2,
  5. Tetsushi Furukawa4,
  6. Kohei Sawada3,
  7. Seiryo Sugiura1,2 and
  8. Toshiaki Hisada1,2
  1. 1Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8563, Japan.
  2. 2UT-Heart Inc., 3-25-8 Nozawa, Setagaya-ku, Tokyo 154-0003, Japan.
  3. 3Global CV Assessment, Eisai Co. Ltd., Tokodai 5-1-3, Tsukua-shi, Ibaraki 300-2635, Japan.
  4. 4Department of Bio-informational Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.
  1. *Corresponding author. E-mail: okada{at}sml.k.u-tokyo.ac.jp

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