Research ArticleSTRUCTURAL BIOLOGY

Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors

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Science Advances  24 Jul 2015:
Vol. 1, no. 6, e1500107
DOI: 10.1126/sciadv.1500107

Article Information

vol. 1 no. 6

Online ISSN: 
History: 
  • Received for publication February 12, 2015
  • Accepted for publication June 4, 2015
  • .

Author Information

  1. Jiyuan Ke1,2,*,
  2. Honglei Ma1,2,*,
  3. Xin Gu2,
  4. Adam Thelen2,,
  5. Joseph S. Brunzelle3,
  6. Jiayang Li4,
  7. H. Eric Xu1,2, and
  8. Karsten Melcher1,2,
  1. 1Key Laboratory of Receptor Research, VARI-SIMM Center, Center for Structure and Function of Drug Targets, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 201203, People’s Republic of China.
  2. 2Laboratory of Structural Sciences and Laboratory of Structural Biology and Biochemistry, Van Andel Research Institute, 333 Bostwick Avenue Northeast, Grand Rapids, MI 49503, USA.
  3. 3Department of Molecular Pharmacology and Biological Chemistry, Life Sciences Collaborative Access Team, Synchrotron Research Center, Northwestern University, Argonne, IL 60439, USA.
  4. 4State Key Laboratory of Plant Genomics and National Center for Plant Gene Research (Beijing), Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, People’s Republic of China.
  1. Corresponding author. E-mail: eric.xu{at}vai.org (H.E.X.); karsten.melcher{at}vai.org (K.M.)
    • * These authors contributed equally to this work.

    • Present address: Michigan State University, East Lansing, MI 48824, USA.

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