Research ArticleONCOLOGY

MED12 methylation by CARM1 sensitizes human breast cancer cells to chemotherapy drugs

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Science Advances  09 Oct 2015:
Vol. 1, no. 9, e1500463
DOI: 10.1126/sciadv.1500463

Article Information

vol. 1 no. 9

Online ISSN: 
History: 
  • Received for publication April 13, 2015
  • Accepted for publication August 10, 2015

Author Information

  1. Lu Wang1,*,
  2. Hao Zeng1,2,*,
  3. Qiang Wang1,3,4,
  4. Zibo Zhao1,
  5. Thomas G. Boyer5,
  6. Xiuwu Bian3,4 and
  7. Wei Xu1,2,
  1. 1McArdle Laboratory for Cancer Research, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.
  2. 2Graduate Program in Cellular and Molecular Biology, University of Wisconsin–Madison, Madison, WI 53705, USA.
  3. 3Institute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.
  4. 4Key Laboratory of Tumor Immunopathology, Ministry of Education of China, Chongqing 400038, China.
  5. 5Department of Molecular Medicine, Institute of Biotechnology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229–3900, USA.
  1. Corresponding author. E-mail: wxu{at}oncology.wisc.edu
    • * These authors contributed equally to this work.

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