Research ArticleBIOCHEMISTRY
A novel persulfide detection method reveals protein persulfide- and polysulfide-reducing functions of thioredoxin and glutathione systems
- Éva Dóka1,
- Irina Pader2,
- Adrienn Bíró1,
- Katarina Johansson2,
- Qing Cheng2,
- Krisztina Ballagó1,
- View ORCID ProfileJustin R. Prigge3,
- View ORCID ProfileDaniel Pastor-Flores4,
- Tobias P. Dick4,
- View ORCID ProfileEdward E. Schmidt3,
- View ORCID ProfileElias S. J. Arnér2 and
- Péter Nagy1,*
- 1Department of Molecular Immunology and Toxicology, National Institute of Oncology, Ráth György utca 7-9, Budapest 1122, Hungary.
- 2Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-171 77 Stockholm, Sweden.
- 3Department of Microbiology and Immunology, Montana State University, Cooley Hall, PO Box 173520, Bozeman, MT 59717, USA.
- 4Division of Redox Regulation, German Cancer Research Center (DKFZ), DKFZ-ZMBH Alliance, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
- ↵*Corresponding author. E-mail: peter.nagy{at}oncol.hu
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Science Advances 22 Jan 2016:
Vol. 2, no. 1, e1500968
DOI: 10.1126/sciadv.1500968
Vol. 2, no. 1, e1500968
DOI: 10.1126/sciadv.1500968
Éva Dóka
1Department of Molecular Immunology and Toxicology, National Institute of Oncology, Ráth György utca 7-9, Budapest 1122, Hungary.
Irina Pader
2Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-171 77 Stockholm, Sweden.
Adrienn Bíró
1Department of Molecular Immunology and Toxicology, National Institute of Oncology, Ráth György utca 7-9, Budapest 1122, Hungary.
Katarina Johansson
2Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-171 77 Stockholm, Sweden.
Qing Cheng
2Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-171 77 Stockholm, Sweden.
Krisztina Ballagó
1Department of Molecular Immunology and Toxicology, National Institute of Oncology, Ráth György utca 7-9, Budapest 1122, Hungary.
Justin R. Prigge
3Department of Microbiology and Immunology, Montana State University, Cooley Hall, PO Box 173520, Bozeman, MT 59717, USA.
Daniel Pastor-Flores
4Division of Redox Regulation, German Cancer Research Center (DKFZ), DKFZ-ZMBH Alliance, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Tobias P. Dick
4Division of Redox Regulation, German Cancer Research Center (DKFZ), DKFZ-ZMBH Alliance, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Edward E. Schmidt
3Department of Microbiology and Immunology, Montana State University, Cooley Hall, PO Box 173520, Bozeman, MT 59717, USA.
Elias S. J. Arnér
2Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-171 77 Stockholm, Sweden.
Péter Nagy
1Department of Molecular Immunology and Toxicology, National Institute of Oncology, Ráth György utca 7-9, Budapest 1122, Hungary.
