Research ArticleBIOCHEMISTRY
A novel persulfide detection method reveals protein persulfide- and polysulfide-reducing functions of thioredoxin and glutathione systems
- Éva Dóka1,
- Irina Pader2,
- Adrienn Bíró1,
- Katarina Johansson2,
- Qing Cheng2,
- Krisztina Ballagó1,
- Justin R. Prigge3,
- Daniel Pastor-Flores4,
- Tobias P. Dick4,
- Edward E. Schmidt3,
- Elias S. J. Arnér2 and
- Péter Nagy1,*
- 1Department of Molecular Immunology and Toxicology, National Institute of Oncology, Ráth György utca 7-9, Budapest 1122, Hungary.
- 2Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-171 77 Stockholm, Sweden.
- 3Department of Microbiology and Immunology, Montana State University, Cooley Hall, PO Box 173520, Bozeman, MT 59717, USA.
- 4Division of Redox Regulation, German Cancer Research Center (DKFZ), DKFZ-ZMBH Alliance, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
- ↵*Corresponding author. E-mail: peter.nagy{at}oncol.hu
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Science Advances 22 Jan 2016:
Vol. 2, no. 1, e1500968
DOI: 10.1126/sciadv.1500968
Vol. 2, no. 1, e1500968
DOI: 10.1126/sciadv.1500968
Éva Dóka
Department of Molecular Immunology and Toxicology, National Institute of Oncology, Ráth György utca 7-9, Budapest 1122, Hungary.
Irina Pader
Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-171 77 Stockholm, Sweden.
Adrienn Bíró
Department of Molecular Immunology and Toxicology, National Institute of Oncology, Ráth György utca 7-9, Budapest 1122, Hungary.
Katarina Johansson
Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-171 77 Stockholm, Sweden.
Qing Cheng
Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-171 77 Stockholm, Sweden.
Krisztina Ballagó
Department of Molecular Immunology and Toxicology, National Institute of Oncology, Ráth György utca 7-9, Budapest 1122, Hungary.
Justin R. Prigge
Department of Microbiology and Immunology, Montana State University, Cooley Hall, PO Box 173520, Bozeman, MT 59717, USA.
Daniel Pastor-Flores
Division of Redox Regulation, German Cancer Research Center (DKFZ), DKFZ-ZMBH Alliance, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Tobias P. Dick
Division of Redox Regulation, German Cancer Research Center (DKFZ), DKFZ-ZMBH Alliance, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Edward E. Schmidt
Department of Microbiology and Immunology, Montana State University, Cooley Hall, PO Box 173520, Bozeman, MT 59717, USA.
Elias S. J. Arnér
Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-171 77 Stockholm, Sweden.
Péter Nagy
Department of Molecular Immunology and Toxicology, National Institute of Oncology, Ráth György utca 7-9, Budapest 1122, Hungary.
