Research ArticleBIOCHEMISTRY

Structure and mechanism of human PrimPol, a DNA polymerase with primase activity

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Science Advances  21 Oct 2016:
Vol. 2, no. 10, e1601317
DOI: 10.1126/sciadv.1601317

Article Information

vol. 2 no. 10

Online ISSN: 
History: 
  • Received for publication June 10, 2016
  • Accepted for publication September 19, 2016

Author Information

  1. Olga Rechkoblit1,*,
  2. Yogesh K. Gupta1,*,
  3. Radhika Malik1,*,
  4. Kanagalaghatta R. Rajashankar2,3,
  5. Robert E. Johnson4,
  6. Louise Prakash4,
  7. Satya Prakash4 and
  8. Aneel K. Aggarwal1,
  1. 1Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, Box 1677, 1425 Madison Avenue, New York, NY 10029, USA.
  2. 2Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA.
  3. 3Northeastern Collaborative Access Team, Advanced Photon Source, Argonne National Laboratory, Argonne, IL 60439, USA.
  4. 4Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77755–1061, USA.
  1. Corresponding author. Email: aneel.aggarwal{at}mssm.edu
    • * These authors contributed equally to this work.

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