Research ArticleCOMPUTATIONAL CHEMISTRY

Regulation of protein-ligand binding affinity by hydrogen bond pairing

See allHide authors and affiliations

Science Advances  25 Mar 2016:
Vol. 2, no. 3, e1501240
DOI: 10.1126/sciadv.1501240

Article Information

vol. 2 no. 3

Online ISSN: 
History: 
  • Received for publication September 9, 2015
  • Accepted for publication February 5, 2016
  • .

Author Information

  1. Deliang Chen1,*,
  2. Numan Oezguen2,3,
  3. Petri Urvil2,3,
  4. Colin Ferguson4,
  5. Sara M. Dann5 and
  6. Tor C. Savidge2,3,*
  1. 1Key Laboratory of Organo-Pharmaceutical Chemistry of Jiangxi Province, Chemistry and Chemical Engineering College, Gannan Normal University, Ganzhou, Jiangxi 341000, P. R. China.
  2. 2Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
  3. 3Texas Children’s Microbiome Center, Texas Children’s Hospital, Houston, TX 77030, USA.
  4. 4Echelon Biosciences Inc., Salt Lake City, UT 84108, USA.
  5. 5Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX 77555, USA.
  1. *Corresponding author. E-mail: dechen{at}gnnu.cn (D.C.); tor.savidge{at}bcm.edu (T.C.S.)

Altmetric

Article usage

Article usage: March 2016 to October 2019

AbstractFullPdf
Mar 2016953323363
Apr 2016422162251
May 2016119048140
Jun 201612761101
Jul 20161227684
Aug 20161609649
Sep 20161407237
Oct 20161309164
Nov 201613610265
Dec 20161049046
Jan 2017809045
Feb 2017648856
Mar 2017748751
Apr 20171119836
May 2017878839
Jun 2017758528
Jul 2017538130
Aug 2017657931
Sep 2017606439
Oct 2017716044
Nov 2017817840
Dec 2017889951
Jan 20187111245
Feb 2018528847
Mar 20186913338
Apr 20187214063
May 20185615479
Jun 20186712444
Jul 2018478640
Aug 2018016048
Sep 2018023469
Oct 2018029668
Nov 2018031229
Dec 2018029744
Jan 2019536362
Feb 20191521640
Mar 2019918145
Apr 2019719742
May 2019316348
Jun 2019718349
Jul 2019819378
Aug 20191113034
Sep 2019512342
Oct 201937421

Navigate This Article