Research ArticleMICROBIOLOGY

A three-dimensional culture system recapitulates placental syncytiotrophoblast development and microbial resistance

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Science Advances  04 Mar 2016:
Vol. 2, no. 3, e1501462
DOI: 10.1126/sciadv.1501462

Article Information

vol. 2 no. 3

Online ISSN: 
History: 
  • Received for publication October 14, 2015
  • Accepted for publication January 4, 2016

Author Information

  1. Cameron A. McConkey1,*,
  2. Elizabeth Delorme-Axford1,,
  3. Cheryl A. Nickerson2,
  4. Kwang Sik Kim3,
  5. Yoel Sadovsky1,4,
  6. Jon P. Boyle5 and
  7. Carolyn B. Coyne1,4,
  1. 1Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA 15219, USA.
  2. 2The Biodesign Institute, Center for Infectious Diseases and Vaccinology, Arizona State University, Tempe, AZ 85287, USA.
  3. 3Division of Infectious Diseases, The Johns Hopkins University, Baltimore, MD 21218, USA.
  4. 4Magee-Womens Research Institute, Department of Obstetrics, Gynecology, and Reproductive Science, University of Pittsburgh, Pittsburgh, PA 15213, USA.
  5. 5Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA.
  1. Corresponding author. E-mail: coynec2{at}pitt.edu
  • * Present address: Immunology Graduate Group, University of Pennsylvania, Philadelphia, PA 19104, USA.

  • Present address: Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.

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