Research ArticleVIROLOGY

PPM1A silences cytosolic RNA sensing and antiviral defense through direct dephosphorylation of MAVS and TBK1

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Science Advances  01 Jul 2016:
Vol. 2, no. 7, e1501889
DOI: 10.1126/sciadv.1501889

Article Information

vol. 2 no. 7

Online ISSN: 
History: 
  • Received for publication December 24, 2015
  • Accepted for publication May 31, 2016
  • .

Author Information

  1. Weiwen Xiang1,*,
  2. Qian Zhang1,*,
  3. Xia Lin2,
  4. Shiying Wu1,
  5. Yao Zhou3,
  6. Fansen Meng1,
  7. Yunyun Fan1,
  8. Tao Shen2,
  9. Mu Xiao1,
  10. Zongping Xia1,
  11. Jian Zou3,
  12. Xin-Hua Feng1,2, and
  13. Pinglong Xu1,
  1. 1Life Sciences Institute and Innovation Center for Cell Signaling Network, Zhejiang University, Hangzhou 310058, China.
  2. 2Michael E. DeBakey Department of Surgery and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.
  3. 3Eye Center of the Second Affiliated Hospital School of Medicine, Institute of Translational Medicine, Zhejiang University, Hangzhou 310058, China.
  1. Corresponding author. Email: xhfeng{at}zju.edu.cn (X.-H.F.); xupl{at}zju.edu.cn (P.X.)
    • * These authors contributed equally to this work.

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