Research ArticleHEALTH AND MEDICINE

Targeting macrophage necroptosis for therapeutic and diagnostic interventions in atherosclerosis

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Science Advances  22 Jul 2016:
Vol. 2, no. 7, e1600224
DOI: 10.1126/sciadv.1600224

Article Information

vol. 2 no. 7

Online ISSN: 
History: 
  • Received for publication February 6, 2016
  • Accepted for publication June 24, 2016
  • .

Author Information

  1. Denuja Karunakaran1,
  2. Michele Geoffrion1,
  3. Lihui Wei1,2,
  4. Wei Gan1,2,
  5. Laura Richards1,
  6. Prakriti Shangari1,
  7. Ella M. DeKemp1,
  8. Rachelle A. Beanlands1,
  9. Ljubica Perisic3,
  10. Lars Maegdefessel4,
  11. Ulf Hedin3,
  12. Subash Sad5,
  13. Liang Guo6,
  14. Frank D. Kolodgie6,
  15. Renu Virmani6,
  16. Terrence Ruddy1,2 and
  17. Katey J. Rayner1,5,*
  1. 1University of Ottawa Heart Institute, Ottawa, Ontario K1Y4W7, Canada.
  2. 2Canadian Molecular Imaging Centre of Excellence, University of Ottawa Heart Institute, Ottawa, Ontario K1Y4W7, Canada.
  3. 3Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm 171 76, Sweden.
  4. 4Department of Medicine, Karolinska Institute, Stockholm 171 76, Sweden.
  5. 5Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario K1H8L1, Canada.
  6. 6CVPath Institute Inc., Gaithersburg, MD 20878, USA.
  1. *Corresponding author. Email: krayner{at}ottawaheart.ca

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