Research ArticleHEALTH AND MEDICINE
Raman spectroscopy imaging reveals interplay between atherosclerosis and medial calcification in the human aorta
- View ORCID ProfileAmanda Y. F. You1,2,3,
- Mads S. Bergholt1,2,3,
- Jean-Philippe St-Pierre1,2,3,*,
- View ORCID ProfileWorrapong Kit-Anan1,2,3,
- View ORCID ProfileIsaac J. Pence1,2,3,
- View ORCID ProfileAdrian H. Chester4,
- Magdi H. Yacoub4,
- View ORCID ProfileSergio Bertazzo5 and
- View ORCID ProfileMolly M. Stevens1,2,3,†
- 1Department of Materials, Imperial College London, London SW7 2AZ, UK.
- 2Department of Bioengineering, Imperial College London, London SW7 2AZ, UK.
- 3Institute of Biomedical Engineering, Imperial College London, London SW7 2AZ, UK.
- 4National Heart and Lung Institute, Harefield Heart Science Centre, Imperial College London, Harefield, Middlesex UB9 6JH, UK.
- 5Department of Medical Physics and Biomedical Engineering, University College London, Malet Place Engineering Building, London WC1E 6BT, UK.
- ↵†Corresponding author. Email: m.stevens{at}imperial.ac.uk
↵* Present address: Department of Chemical and Biological Engineering, University of Ottawa, Ottawa K1N 6N5, Canada.
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Science Advances 06 Dec 2017:
Vol. 3, no. 12, e1701156
DOI: 10.1126/sciadv.1701156
Vol. 3, no. 12, e1701156
DOI: 10.1126/sciadv.1701156
Amanda Y. F. You
1Department of Materials, Imperial College London, London SW7 2AZ, UK.
2Department of Bioengineering, Imperial College London, London SW7 2AZ, UK.
3Institute of Biomedical Engineering, Imperial College London, London SW7 2AZ, UK.
Mads S. Bergholt
1Department of Materials, Imperial College London, London SW7 2AZ, UK.
2Department of Bioengineering, Imperial College London, London SW7 2AZ, UK.
3Institute of Biomedical Engineering, Imperial College London, London SW7 2AZ, UK.
Jean-Philippe St-Pierre
1Department of Materials, Imperial College London, London SW7 2AZ, UK.
2Department of Bioengineering, Imperial College London, London SW7 2AZ, UK.
3Institute of Biomedical Engineering, Imperial College London, London SW7 2AZ, UK.
Worrapong Kit-Anan
1Department of Materials, Imperial College London, London SW7 2AZ, UK.
2Department of Bioengineering, Imperial College London, London SW7 2AZ, UK.
3Institute of Biomedical Engineering, Imperial College London, London SW7 2AZ, UK.
Isaac J. Pence
1Department of Materials, Imperial College London, London SW7 2AZ, UK.
2Department of Bioengineering, Imperial College London, London SW7 2AZ, UK.
3Institute of Biomedical Engineering, Imperial College London, London SW7 2AZ, UK.
Adrian H. Chester
4National Heart and Lung Institute, Harefield Heart Science Centre, Imperial College London, Harefield, Middlesex UB9 6JH, UK.
Magdi H. Yacoub
4National Heart and Lung Institute, Harefield Heart Science Centre, Imperial College London, Harefield, Middlesex UB9 6JH, UK.
Sergio Bertazzo
5Department of Medical Physics and Biomedical Engineering, University College London, Malet Place Engineering Building, London WC1E 6BT, UK.
Molly M. Stevens
1Department of Materials, Imperial College London, London SW7 2AZ, UK.
2Department of Bioengineering, Imperial College London, London SW7 2AZ, UK.
3Institute of Biomedical Engineering, Imperial College London, London SW7 2AZ, UK.