Research ArticleORGANIC CHEMISTRY
A Rh(II)-catalyzed multicomponent reaction by trapping an α-amino enol intermediate in a traditional two-component reaction pathway
- Shunying Liu1,
- Wenfeng Yao1,
- Yuan Liu1,2,
- Qinghua Wei1,
- Jianghui Chen1,
- Xiang Wu1,
- Fei Xia1,2,* and
- Wenhao Hu1,*
- 1Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, 3663 North Zhongshan Road, Shanghai 200062, China.
- 2New York University (NYU)–East China Normal University Center for Computational Chemistry at NYU Shanghai, Shanghai 200062, China.
- ↵*Corresponding author. Email: whu{at}chem.ecnu.edu.cn (W.H.); fxia{at}chem.ecnu.edu.cn (F.X.)
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Science Advances 08 Mar 2017:
Vol. 3, no. 3, e1602467
DOI: 10.1126/sciadv.1602467
Vol. 3, no. 3, e1602467
DOI: 10.1126/sciadv.1602467
Shunying Liu
1Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, 3663 North Zhongshan Road, Shanghai 200062, China.
Wenfeng Yao
1Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, 3663 North Zhongshan Road, Shanghai 200062, China.
Yuan Liu
1Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, 3663 North Zhongshan Road, Shanghai 200062, China.
2New York University (NYU)–East China Normal University Center for Computational Chemistry at NYU Shanghai, Shanghai 200062, China.
Qinghua Wei
1Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, 3663 North Zhongshan Road, Shanghai 200062, China.
Jianghui Chen
1Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, 3663 North Zhongshan Road, Shanghai 200062, China.
Xiang Wu
1Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, 3663 North Zhongshan Road, Shanghai 200062, China.
Fei Xia
1Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, 3663 North Zhongshan Road, Shanghai 200062, China.
2New York University (NYU)–East China Normal University Center for Computational Chemistry at NYU Shanghai, Shanghai 200062, China.
Wenhao Hu
1Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, 3663 North Zhongshan Road, Shanghai 200062, China.
