Research ArticleBIOPHYSICS

Label-free optical detection of single enzyme-reactant reactions and associated conformational changes

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Science Advances  29 Mar 2017:
Vol. 3, no. 3, e1603044
DOI: 10.1126/sciadv.1603044

Article Information

vol. 3 no. 3

Online ISSN: 
History: 
  • Received for publication December 5, 2016
  • Accepted for publication March 9, 2017

Author Information

  1. Eugene Kim*,,
  2. Martin D. Baaske*,,
  3. Isabel Schuldes,,
  4. Peter S. Wilsch and
  5. Frank Vollmer*,§
  1. Max Planck Institute for the Science of Light, Staudtstrasse 2, 91058 Erlangen, Germany.
  1. *Corresponding author. Email: eugene.kim{at}mpl.mpg.de (E.K.); martin.baaske{at}mpl.mpg.de (M.D.B.); f.vollmer{at}exeter.ac.uk (F.V.)
    • These authors contributed equally to this work.

    • Present address: Chair for Crystallography and Structural Physics, University of Erlangen-Nuremberg, Staudtstrasse 3, Erlangen, Germany.

    • § Present address: Living Systems Institute, School of Physics, University of Exeter, Exeter EX4 4QD, U.K.

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