Research ArticleMOLECULAR NEUROSCIENCE

Selective targeting of primary and secondary nucleation pathways in Aβ42 aggregation using a rational antibody scanning method

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Science Advances  21 Jun 2017:
Vol. 3, no. 6, e1700488
DOI: 10.1126/sciadv.1700488

Article Information

vol. 3 no. 6

Online ISSN: 
History: 
  • Received for publication February 14, 2017
  • Accepted for publication April 26, 2017
  • .

Author Information

  1. Francesco A. Aprile1,
  2. Pietro Sormanni1,
  3. Michele Perni1,
  4. Paolo Arosio2,
  5. Sara Linse3,
  6. Tuomas P. J. Knowles1,
  7. Christopher M. Dobson1 and
  8. Michele Vendruscolo1,*
  1. 1Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.
  2. 2Department of Chemistry and Applied Biosciences, ETH Zurich, 8093 Zurich, Switzerland.
  3. 3Department of Biochemistry and Structural Biology, Center for Molecular Protein Science, Lund University, 221 00 Lund, Sweden.
  1. *Corresponding author. Email: mv245{at}cam.ac.uk

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