Research ArticleMICROBIOLOGY
A viral scaffolding protein triggers portal ring oligomerization and incorporation during procapsid assembly
- Tina Motwani1,
- Ravi K. Lokareddy2,
- Carmen A. Dunbar3,
- Juliana R. Cortines1,*,
- Martin F. Jarrold3,
- Gino Cingolani2,4 and
- Carolyn M. Teschke1,5,†
- 1Department of Molecular and Cell Biology, University of Connecticut, 91 North Eagleville Road, Storrs, CT 06269, USA.
- 2Department of Biochemistry and Molecular Biology, Thomas Jefferson University, 233 South 10th Street, Philadelphia, PA 19107, USA.
- 3Department of Chemistry, Indiana University, 800 East Kirkwood Avenue, Bloomington, IN 47405, USA.
- 4Institute of Biomembranes and Bioenergetics, National Research Council, Via Amendola 165/A, 70126 Bari, Italy.
- 5Department of Chemistry, University of Connecticut, Storrs, CT 06269, USA.
- ↵†Corresponding author. Email: carolyn.teschke{at}uconn.edu
↵* Present address: Departamento de Virologia, Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro, CEP 21941-902, Rio de Janeiro, Brazil.
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Science Advances 26 Jul 2017:
Vol. 3, no. 7, e1700423
DOI: 10.1126/sciadv.1700423
Vol. 3, no. 7, e1700423
DOI: 10.1126/sciadv.1700423
Tina Motwani
1Department of Molecular and Cell Biology, University of Connecticut, 91 North Eagleville Road, Storrs, CT 06269, USA.
Ravi K. Lokareddy
2Department of Biochemistry and Molecular Biology, Thomas Jefferson University, 233 South 10th Street, Philadelphia, PA 19107, USA.
Carmen A. Dunbar
3Department of Chemistry, Indiana University, 800 East Kirkwood Avenue, Bloomington, IN 47405, USA.
Juliana R. Cortines
1Department of Molecular and Cell Biology, University of Connecticut, 91 North Eagleville Road, Storrs, CT 06269, USA.
Martin F. Jarrold
3Department of Chemistry, Indiana University, 800 East Kirkwood Avenue, Bloomington, IN 47405, USA.
Gino Cingolani
2Department of Biochemistry and Molecular Biology, Thomas Jefferson University, 233 South 10th Street, Philadelphia, PA 19107, USA.
4Institute of Biomembranes and Bioenergetics, National Research Council, Via Amendola 165/A, 70126 Bari, Italy.
Carolyn M. Teschke
1Department of Molecular and Cell Biology, University of Connecticut, 91 North Eagleville Road, Storrs, CT 06269, USA.
5Department of Chemistry, University of Connecticut, Storrs, CT 06269, USA.
