Research ArticleHEALTH AND MEDICINE

Microphysiological 3D model of amyotrophic lateral sclerosis (ALS) from human iPS-derived muscle cells and optogenetic motor neurons

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Science Advances  10 Oct 2018:
Vol. 4, no. 10, eaat5847
DOI: 10.1126/sciadv.aat5847

Article Information

vol. 4 no. 10

Online ISSN: 
History: 
  • Received for publication March 14, 2018
  • Accepted for publication September 5, 2018
  • .

Author Information

  1. Tatsuya Osaki1,
  2. Sebastien G. M. Uzel1,2,3 and
  3. Roger D. Kamm1,4,5,*
  1. 1Department of Mechanical Engineering, Massachusetts Institute of Technology, 500 Technology Square, Room NE47-321, Cambridge, MA 02139, USA.
  2. 2Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, MA 02138, USA.
  3. 3John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA.
  4. 4Department of Biological Engineering, Massachusetts Institute of Technology, 500 Technology Square, Room NE47-321, Cambridge, MA 02139, USA.
  5. 5BioSystems and Micromechanics (BioSyM) IRG, Singapore-MIT Alliance for Research and Technology, Singapore, Singapore.
  1. *Corresponding author. Email: rdkamm{at}mit.edu

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Oct 2018088572044
Nov 201801317432
Dec 201801019257
Jan 201931664187
Feb 201955585185
Mar 201950586226
Apr 201919444114
May 20193620177
Jun 201912518123
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Aug 201939374181
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