Research ArticleIMMUNOLOGY

A tyrosine sulfation–dependent HLA-I modification identifies memory B cells and plasma cells

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Science Advances  07 Nov 2018:
Vol. 4, no. 11, eaar7653
DOI: 10.1126/sciadv.aar7653

Article Information

vol. 4 no. 11

Online ISSN: 
History: 
  • Received for publication December 14, 2017
  • Accepted for publication October 12, 2018
  • .

Author Information

  1. Justin T. H. Chan1,*,
  2. Yanling Liu1,*,
  3. Srijit Khan1,*,
  4. Jonathan R. St-Germain2,
  5. Chunxia Zou3,
  6. Leslie Y. T. Leung1,
  7. Judi Yang1,
  8. Mengyao Shi1,
  9. Eyal Grunebaum4,
  10. Paolo Campisi5,
  11. Evan J. Propst5,
  12. Theresa Holler5,
  13. Amit Bar-Or6,
  14. Joan E. Wither1,
  15. Christopher W. Cairo3,
  16. Michael F. Moran2,
  17. Alexander F. Palazzo7,
  18. Max D. Cooper8 and
  19. Götz R. A. Ehrhardt1,
  1. 1Department of Immunology, University of Toronto, Toronto, ON, Canada.
  2. 2Department of Molecular Genetics, Hospital for Sick Children, Toronto, ON, Canada.
  3. 3Alberta Glycomics Centre and Department of Chemistry, University of Alberta, Edmonton, AB, Canada.
  4. 4Division of Immunology and Allergy, Hospital for Sick Children and University of Toronto, Toronto, ON, Canada.
  5. 5Department of Otolaryngology-Head and Neck Surgery, Hospital for Sick Children and University of Toronto, Toronto, ON, Canada.
  6. 6Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.
  7. 7Department of Biochemistry, University of Toronto, Toronto, ON, Canada.
  8. 8Department of Pathology and Laboratory Medicine and Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.
  1. Corresponding author. Email: goetz.ehrhardt{at}utoronto.ca
  • * These authors contributed equally to this work.

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