Research ArticleCELL BIOLOGY

Strain-triggered mechanical feedback in self-organizing optic-cup morphogenesis

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Science Advances  21 Nov 2018:
Vol. 4, no. 11, eaau1354
DOI: 10.1126/sciadv.aau1354

Article Information

vol. 4 no. 11

Online ISSN: 
History: 
  • Received for publication May 9, 2018
  • Accepted for publication October 19, 2018
  • .

Author Information

  1. S. Okuda1,2,3,*,
  2. N. Takata1,,
  3. Y. Hasegawa1,,
  4. M. Kawada1,
  5. Y. Inoue3,
  6. T. Adachi3,
  7. Y. Sasai3,§ and
  8. M. Eiraku1,3,*
  1. 1RIKEN Center for Developmental Biology, Kobe 650-0047, Japan.
  2. 2PRESTO, Japan Science and Technology Agency, Kawaguchi 332-0012, Japan.
  3. 3Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.
  1. *Corresponding author. Email: eiraku{at}infront.kyoto-u.ac.jp (M.E.); satoru.okuda{at}riken.jp (S.O.)
  • Present address: Center for Vascular and Developmental Biology, Feinberg Cardiovascular Research Institute, Northwestern University Chicago, IL 60611, USA.

  • Present address: Department of Neurology, Children’s Hospital of Philadelphia Research Institute, Philadelphia, PA 19104, USA.

  • § Deceased.

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