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Deciphering and engineering chromodomain-methyllysine peptide recognition

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Science Advances  07 Nov 2018:
Vol. 4, no. 11, eaau1447
DOI: 10.1126/sciadv.aau1447

Article Information

vol. 4 no. 11

Online ISSN: 
History: 
  • Received for publication May 10, 2018
  • Accepted for publication September 24, 2018
  • .

Author Information

  1. Ryan Hard1,*,
  2. Nan Li1,*,
  3. Wei He1,*,,
  4. Brian Ross2,3,
  5. Gary C. H. Mo2,
  6. Qin Peng4,
  7. Richard S. L. Stein1,,
  8. Elizabeth Komives1,
  9. Yingxiao Wang4,
  10. Jin Zhang2,5 and
  11. Wei Wang1,6,§
  1. 1Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA.
  2. 2Department of Pharmacology, University of California, San Diego, La Jolla, CA, 92093, USA.
  3. 3Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
  4. 4Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA.
  5. 5Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  6. 6Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  1. §Corresponding author. Email: wei-wang{at}ucsd.edu
  • * These authors contributed equally to this work.

  • Present address: Polypeptide Group, 365 Maple Ave., Torrance, CA 90503, USA.

  • Present address: Microsoft Corporation, 14855 NE 36th Street, Redmond, WA 98052, USA.

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