Research ArticleVIROLOGY
Triterpenoids manipulate a broad range of virus-host fusion via wrapping the HR2 domain prevalent in viral envelopes
- View ORCID ProfileLonglong Si1,
- Kun Meng1,
- Zhenyu Tian1,
- Jiaqi Sun1,
- Huiqiang Li1,
- Ziwei Zhang1,
- Veronica Soloveva2,
- Haiwei Li1,
- Ge Fu1,
- Qing Xia1,
- Sulong Xiao1,
- Lihe Zhang1 and
- View ORCID ProfileDemin Zhou1,*
- 1State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Beijing 100191, China.
- 2U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702, USA.
- ↵*Corresponding author. Email: deminzhou{at}bjmu.edu.cn
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Science Advances 21 Nov 2018:
Vol. 4, no. 11, eaau8408
DOI: 10.1126/sciadv.aau8408
Vol. 4, no. 11, eaau8408
DOI: 10.1126/sciadv.aau8408
Longlong Si
1State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Beijing 100191, China.
Kun Meng
1State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Beijing 100191, China.
Zhenyu Tian
1State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Beijing 100191, China.
Jiaqi Sun
1State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Beijing 100191, China.
Huiqiang Li
1State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Beijing 100191, China.
Ziwei Zhang
1State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Beijing 100191, China.
Veronica Soloveva
2U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702, USA.
Haiwei Li
1State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Beijing 100191, China.
Ge Fu
1State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Beijing 100191, China.
Qing Xia
1State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Beijing 100191, China.
Sulong Xiao
1State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Beijing 100191, China.
Lihe Zhang
1State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Beijing 100191, China.
Demin Zhou
1State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Beijing 100191, China.