Research ArticleCELL BIOLOGY

RAB7A phosphorylation by TBK1 promotes mitophagy via the PINK-PARKIN pathway

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Science Advances  21 Nov 2018:
Vol. 4, no. 11, eaav0443
DOI: 10.1126/sciadv.aav0443

Article Information

vol. 4 no. 11

Online ISSN: 
History: 
  • Received for publication August 12, 2018
  • Accepted for publication October 19, 2018
  • .

Author Information

  1. J.-M. Heo1,
  2. A. Ordureau1,
  3. S. Swarup1,
  4. J. A. Paulo1,
  5. K. Shen2,3,4,5,
  6. D. M. Sabatini2,3,4,5 and
  7. J. W. Harper1,*
  1. 1Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
  2. 2Whitehead Institute for Biomedical Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
  3. 3Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  4. 4Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
  5. 5Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.
  1. *Corresponding author. Email: wade_harper{at}hms.harvard.edu

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