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Autoregulation of von Willebrand factor function by a disulfide bond switch

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Science Advances  28 Feb 2018:
Vol. 4, no. 2, eaaq1477
DOI: 10.1126/sciadv.aaq1477

Article Information

vol. 4 no. 2

Online ISSN: 
History: 
  • Received for publication October 6, 2017
  • Accepted for publication January 30, 2018

Author Information

  1. Diego Butera1,
  2. Freda Passam2,
  3. Lining Ju3,
  4. Kristina M. Cook1,
  5. Heng Woon1,
  6. Camilo Aponte-Santamaría4,5,*,
  7. Elizabeth Gardiner6,
  8. Amanda K. Davis7,
  9. Deirdre A. Murphy8,
  10. Agnieszka Bronowska4,
  11. Brenda M. Luken9,,
  12. Carsten Baldauf10,
  13. Shaun Jackson3,
  14. Robert Andrews11,
  15. Frauke Gräter4 and
  16. Philip J. Hogg1,12,
  1. 1The Centenary Institute, Newtown, New South Wales, Australia.
  2. 2St George Clinical School, Kogarah, New South Wales, Australia.
  3. 3Heart Research Institute and Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia.
  4. 4Heidelberg Institute for Theoretical Studies, Schloß-Wolfsbrunnenweg 35, Heidelberg, Germany.
  5. 5Interdisciplinary Center for Scientific Computing, Heidelberg University, Heidelberg, Germany.
  6. 6Department of Cancer Biology and Therapeutics, John Curtin School of Medicine, Australian National University, Canberra, Australia.
  7. 7Haematology Unit, Alfred Hospital, Melbourne, Victoria, Australia.
  8. 8Intensive Care Unit, Alfred Hospital, Melbourne, Victoria, Australia.
  9. 9Sanquin Research and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands.
  10. 10Fritz Haber Institute, Faradayweg 4-6, Berlin-Dahlem, Germany.
  11. 11Australian Centre for Blood Diseases, Monash University, Melbourne, Victoria, Australia.
  12. 12National Health and Medical Research Council Clinical Trials Centre, University of Sydney, Sydney, Australia.
  1. Corresponding author. Email: phil.hogg{at}sydney.edu.au
  • * Present address: Max Planck Tandem Group in Computational Biophysics, University of Los Andes, Bogotá, Colombia.

  • Present address: Centre for Haematology, Department of Medicine, Imperial College London, London, UK.

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