Research ArticleSTRUCTURAL BIOLOGY

Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors

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Science Advances  14 Mar 2018:
Vol. 4, no. 3, eaap9714
DOI: 10.1126/sciadv.aap9714

Article Information

vol. 4 no. 3

Online ISSN: 
History: 
  • Received for publication September 18, 2017
  • Accepted for publication February 7, 2018
  • .

Author Information

  1. Ariel Talavera1,2,*,
  2. Jelle Hendrix3,4,*,
  3. Wim Versées1,2,
  4. Dukas Jurėnas5,
  5. Katleen Van Nerom5,
  6. Niels Vandenberk3,
  7. Ranjan Kumar Singh1,2,
  8. Albert Konijnenberg1,2,6,
  9. Steven De Gieter1,2,
  10. Daniel Castro-Roa7,
  11. Anders Barth8,
  12. Henri De Greve1,2,
  13. Frank Sobott6,9,10,
  14. Johan Hofkens3,11,
  15. Nikolay Zenkin7,
  16. Remy Loris1,2, and
  17. Abel Garcia-Pino5,
  1. 1Structural Biology Brussels, Department of Bio-engineering Sciences, Vrije Universiteit Brussel, Brussels, Belgium.
  2. 2Center for Structural Biology, VIB, Flanders, Belgium.
  3. 3Molecular Imaging and Photonics, University of Leuven, B-3001 Leuven, Belgium.
  4. 4Biomedical Research Institute, Hasselt University, B-3590 Hasselt, Belgium.
  5. 5Cellular and Molecular Microbiology, Department of Molecular Biology, Université Libre de Bruxelles, Brussels, Belgium.
  6. 6Biomolecular and Analytical Mass Spectrometry Group, Department of Chemistry, University of Antwerp, Antwerp, Belgium.
  7. 7Centre for Bacterial Cell Biology, Institute for Cell and Molecular Biosciences, Newcastle University, Baddiley-Clark Building, Richardson Road, Newcastle upon Tyne NE2 4AX, UK.
  8. 8Fluorescence Applications in Biology Laboratory, Department of Chemistry and Pharmacy, Ludwig-Maximilians-Universität München, Munich, Germany.
  9. 9School of Molecular and Cellular Biology, University of Leeds, Leeds LS2 9JT, UK.
  10. 10Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK.
  11. 11Nano-Science Center, Department of Chemistry, University of Copenhagen, Universitetsparken 5, 2100 Copenhagen, Denmark.
  1. Corresponding author. Email: remy.loris{at}vub.be (R.L.); agarciap{at}ulb.ac.be (A.G.-P.)
  • * These authors contributed equally to this work.

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