The mechanism of two-phase motility in the spirochete Leptospira: Swimming and crawling

Hajime Tahara; Kyosuke Takabe; Yuya Sasaki; Kie Kasuga; Akihiro Kawamoto; Nobuo Koizumi; Shuichi Nakamura

doi:10.1126/sciadv.aar7975

Research ArticleDISEASES AND DISORDERS

The mechanism of two-phase motility in the spirochete Leptospira: Swimming and crawling

Hajime Tahara¹,
Kyosuke Takabe¹,*,
View ORCID ProfileYuya Sasaki²,³,
View ORCID ProfileKie Kasuga⁴,⁵,
View ORCID ProfileAkihiro Kawamoto⁶,†,
View ORCID ProfileNobuo Koizumi³ and
View ORCID ProfileShuichi Nakamura¹,‡

¹Department of Applied Physics, Graduate School of Engineering, Tohoku University, 6-6-05 Aoba, Aoba-ku, Sendai, Miyagi 980-8579, Japan.
²Graduate School of Bio-Applications and Systems Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo 184-8588, Japan.
³Department of Bacteriology I, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan.
⁴Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, 265-1 Higashijima, Akiha-ku, Niigata City, Niigata 956-8603, Japan.
⁵Division of Medical Sciences, Graduate School of Medicine, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa 920-0934, Japan.
⁶Graduate School of Frontier Biosciences, Osaka University, 1-3 Yamadaoka, Suita, Osaka 565-0871, Japan.

↵‡Corresponding author. Email: naka{at}bp.apph.tohoku.ac.jp

↵* Present address: Department of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8577, Japan.
↵† Present address: Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka 565-0871, Japan.

See allHide authors and affiliations

Science Advances 30 May 2018:
Vol. 4, no. 5, eaar7975
DOI: 10.1126/sciadv.aar7975

Hajime Tahara

1Department of Applied Physics, Graduate School of Engineering, Tohoku University, 6-6-05 Aoba, Aoba-ku, Sendai, Miyagi 980-8579, Japan.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Kyosuke Takabe

1Department of Applied Physics, Graduate School of Engineering, Tohoku University, 6-6-05 Aoba, Aoba-ku, Sendai, Miyagi 980-8579, Japan.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Yuya Sasaki

2Graduate School of Bio-Applications and Systems Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo 184-8588, Japan.

3Department of Bacteriology I, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Yuya Sasaki

Kie Kasuga

4Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, 265-1 Higashijima, Akiha-ku, Niigata City, Niigata 956-8603, Japan.

5Division of Medical Sciences, Graduate School of Medicine, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa 920-0934, Japan.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Kie Kasuga

Akihiro Kawamoto

6Graduate School of Frontier Biosciences, Osaka University, 1-3 Yamadaoka, Suita, Osaka 565-0871, Japan.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Akihiro Kawamoto

Nobuo Koizumi

3Department of Bacteriology I, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Nobuo Koizumi

Shuichi Nakamura

1Department of Applied Physics, Graduate School of Engineering, Tohoku University, 6-6-05 Aoba, Aoba-ku, Sendai, Miyagi 980-8579, Japan.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Shuichi Nakamura
For correspondence: naka@bp.apph.tohoku.ac.jp

Article
Figures & Data
Info & Metrics
eLetters
PDF

eLetters is an online forum for ongoing peer review. Submission of eLetters are open to all . Please read our guidelines before submitting your own eLetter.

Submit a Response to This Article

Compose eLetter

Title

Contents

More information about text formats

Plain text

Plain text
No HTML tags allowed.
Web page addresses and e-mail addresses turn into links automatically.
Lines and paragraphs break automatically.

Author Information

Contributors
First name and middle name First or given name, e.g. 'Peter'. Last Name Your last, or family, name, e.g. 'MacMoody'. Email Your email address, e.g. higgs-boson@gmail.com Role / Occupation Your role and/or occupation, e.g. 'Orthopedic Surgeon'. Affiliation Your organization or institution (if applicable), e.g. 'Royal Free Hospital'.

Statement of Competing Interests

Competing interests?

Yes

Please describe the competing interests

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Vertical Tabs

No eLetters have been published for this article.

View Full Text

The mechanism of two-phase motility in the spirochete Leptospira: Swimming and crawling

Plain text

Vertical Tabs

Science Advances

Article Tools