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Mannan-induced Nos2 in macrophages enhances IL-17–driven psoriatic arthritis by innate lymphocytes

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Science Advances  16 May 2018:
Vol. 4, no. 5, eaas9864
DOI: 10.1126/sciadv.aas9864

Article Information

vol. 4 no. 5

Online ISSN: 
History: 
  • Received for publication January 13, 2018
  • Accepted for publication April 6, 2018
  • .

Author Information

  1. Jianghong Zhong1,
  2. Tatjana Scholz2,
  3. Anthony C. Y. Yau1,
  4. Simon Guerard1,
  5. Ulrike Hüffmeier3,
  6. Harald Burkhardt2 and
  7. Rikard Holmdahl1,4,*
  1. 1Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm 171 77, Sweden.
  2. 2Project Group Translational Medicine and Pharmacology, Fraunhofer Institute for Molecular Biology and Applied Ecology and Division of Rheumatology, University Hospital Frankfurt, Goethe University, Frankfurt am Main 605 90, Germany.
  3. 3Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 910 54, Germany.
  4. 4School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China.
  1. *Corresponding author. Email: rikard.holmdahl{at}ki.se

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