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Plasmodium gametocytes display homing and vascular transmigration in the host bone marrow

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Science Advances  23 May 2018:
Vol. 4, no. 5, eaat3775
DOI: 10.1126/sciadv.aat3775

Article Information

vol. 4 no. 5

Online ISSN: 
History: 
  • Received for publication February 20, 2018
  • Accepted for publication April 12, 2018
  • .

Author Information

  1. Mariana De Niz1,2,3,
  2. Elamaran Meibalan1,
  3. Pedro Mejia1,4,
  4. Siyuan Ma5,
  5. Nicolas M. B. Brancucci1,3,
  6. Carolina Agop-Nersesian6,
  7. Rebecca Mandt1,
  8. Priscilla Ngotho3,
  9. Katie R. Hughes3,
  10. Andrew P. Waters3,
  11. Curtis Huttenhower5,7,
  12. James R. Mitchell4,
  13. Roberta Martinelli8,
  14. Friedrich Frischknecht9,
  15. Karl B. Seydel10,11,
  16. Terrie Taylor10,11,
  17. Danny Milner1,5,12,
  18. Volker T. Heussler2,* and
  19. Matthias Marti1,3,*
  1. 1Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA.
  2. 2Institute of Cell Biology, University of Bern, Baltzerstrasse 4, CH-3012 Bern, Switzerland.
  3. 3Wellcome Trust Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, College of Medical Veterinary and Life Sciences, University of Glasgow, G12 8TA Scotland, UK.
  4. 4Department of Genetics and Complex Diseases, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
  5. 5Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
  6. 6Department of Molecular and Cell Biology, Henry M. Goldman School of Dental Medicine, Boston University, Boston, MA 02118, USA.
  7. 7Broad Institute of Massachusetts Institute of Technology and Harvard, 415 Main Street, Cambridge, MA 02142, USA.
  8. 8Beth Israel Deaconess Medical Centre, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA.
  9. 9Parasitology Centre for Infectious Diseases, University of Heidelberg Medical School, 69120 Heidelberg, Germany.
  10. 10Blantyre Malaria Project, University of Malawi College of Medicine, Blantyre 3, Malawi.
  11. 11College of Osteopathic Medicine, Michigan State University, East Lansing, MI 48824, USA.
  12. 12Department of Pathology, Brigham and Women’s Hospital, 75 Francis Street, Boston, MA 02115, USA.
  1. *Corresponding authors. Email: Matthias.Marti{at}glasgow.ac.uk (M.M.); volker.heussler{at}izb.unibe.ch (V.T.H.)

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