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The neuronal S100B protein is a calcium-tuned suppressor of amyloid-β aggregation

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Science Advances  29 Jun 2018:
Vol. 4, no. 6, eaaq1702
DOI: 10.1126/sciadv.aaq1702

Article Information

vol. 4 no. 6

Online ISSN: 
History: 
  • Received for publication October 13, 2017
  • Accepted for publication May 22, 2018
  • .

Author Information

  1. Joana S. Cristóvão1,2,
  2. Vanessa K. Morris3,4,*,
  3. Isabel Cardoso5,6,
  4. Sónia S. Leal1,2,
  5. Javier Martínez1,2,
  6. Hugo M. Botelho1,
  7. Christoph Göbl3,4,
  8. Rodrigo David1,2,
  9. Katrin Kierdorf7,
  10. Mobina Alemi5,6,8,
  11. Tobias Madl3,4,9,
  12. Günter Fritz7,
  13. Bernd Reif3,4 and
  14. Cláudio M. Gomes1,2,
  1. 1Biosystems and Integrative Sciences Institute, Faculdade de Ciências, Universidade de Lisboa, 1749-016 Lisboa, Portugal.
  2. 2Departamento de Química e Bioquímica, Universidade de Lisboa, 1749-016 Lisboa, Portugal.
  3. 3Center for Integrated Protein Science Munich, Department of Chemistry, Technische Universität München, Lichtenbergstrasse 4, 85748 Garching, Germany.
  4. 4Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany.
  5. 5Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto, Portugal.
  6. 6Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal.
  7. 7Department of Neuropathology, University of Freiburg, Freiburg, Germany.
  8. 8Faculdade de Medicina, Universidade do Porto, Porto, Portugal.
  9. 9Institute of Molecular Biology and Biochemistry, Center of Molecular Medicine, Medical University of Graz, 8010 Graz, Austria.
  1. Corresponding author. Email: cmgomes{at}fc.ul.pt
  • * Present address: Department of Medical Biophysics, Princess Margaret Cancer Centre, University Health Network, 101 College Street, M5G1L7 Toronto, Canada.

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