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Evidence of link between quorum sensing and sugar metabolism in Escherichia coli revealed via cocrystal structures of LsrK and HPr

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Science Advances  01 Jun 2018:
Vol. 4, no. 6, eaar7063
DOI: 10.1126/sciadv.aar7063

Article Information

vol. 4 no. 6

Online ISSN: 
History: 
  • Received for publication December 9, 2017
  • Accepted for publication April 18, 2018
  • .

Author Information

  1. Jung-Hye Ha1,2,3,*,
  2. Pricila Hauk4,5,*,
  3. Kun Cho6,
  4. Yumi Eo1,
  5. Xiaochu Ma7,
  6. Kristina Stephens4,5,
  7. Soyoung Cha1,
  8. Migyeong Jeong8,
  9. Jeong-Yong Suh8,
  10. Herman O. Sintim7,,
  11. William E. Bentley4,5, and
  12. Kyoung-Seok Ryu1,2,
  1. 1Protein Structure Research Group, Korea Basic Science Institute, 162 Yeongudanji-ro, Ochang-eup, Cheongju-si, Chungcheongbuk-do 28119, South Korea.
  2. 2Department of Bio-Analytical Science, University of Science and Technology, 217 Gajeong-ro, Yuseong-gu, Daejeon 34113, South Korea.
  3. 3New Drug Development Center, 80 Cheombok-ro, Dong-gu, Daegu-si 41061, South Korea.
  4. 4Institute for Bioscience and Biotechnology Research, University of Maryland, College Park, MD 20742, USA.
  5. 5Fischell Department of Bioengineering, University of Maryland, College Park, MD 20742, USA.
  6. 6Biomedical Omics Group, Korea Basic Science Institute, Chungcheongbuk-do 28119, South Korea.
  7. 7Department of Chemistry and Institute for Drug Discovery, Purdue University, West Lafayette, IN 47907, USA.
  8. 8Department of Agricultural Biotechnology, Seoul National University, Seoul 08826, South Korea.
  1. Corresponding author. Email: ksryu{at}kbsi.re.kr (K.-S.R.); hsintim{at}purdue.edu (H.O.S.); bentley{at}umd.edu (W.E.B.)
  • * These authors contributed equally to this work.

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